FOG05009
EOG86T1GN
EOG8D254R
sce:NUP159
Genes: 18
EOG86T1GN
EOG8D254R
sce:NUP159
Genes: 18
SGD Description
FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport; regulates ADP release from the ATP-dependent RNA helicase Dbp5p; forms a stable association with Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and Nup116p)
References
Gorsch LC, et al. (1995 May). A conditional allele of the novel repeat-containing yeast nucleoporin RAT7/NUP159 causes both rapid cessation of mRNA export and reversible clustering of nuclear pore complexes.
Belgareh N, et al. (1998 Dec). Functional characterization of a Nup159p-containing nuclear pore subcomplex.
Hurwitz ME, et al. (1998 Sep 15). Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex.
Seedorf M, et al. (1999 Feb). Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase.
Hodge CA, et al. (1999 Oct 15). Rat8p/Dbp5p is a shuttling transport factor that interacts with Rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1-1 cells.
Strässer K, et al. (2000 Aug 21). Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.
Bailer SM, et al. (2000 Aug 4). Nup116p associates with the Nup82p-Nsp1p-Nup159p nucleoporin complex.
Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.
Allen NP, et al. (2001 Aug 3). Proteomic analysis of nucleoporin interacting proteins.
Bailer SM, et al. (2001 Dec). The Nsp1p carboxy-terminal domain is organized into functionally distinct coiled-coil regions required for assembly of nucleoporin subcomplexes and nucleocytoplasmic transport.
Gleizes PE, et al. (2001 Dec 10). Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex.
Allen NP, et al. (2002 Dec). Deciphering networks of protein interactions at the nuclear pore complex.
Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.
Denning DP, et al. (2003 Mar 4). Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded.
Weirich CS, et al. (2004 Dec 3). The N-terminal domain of Nup159 forms a beta-propeller that functions in mRNA export by tethering the helicase Dbp5 to the nuclear pore.
Strawn LA, et al. (2004 Mar). Minimal nuclear pore complexes define FG repeat domains essential for transport.
Yoshida K, et al. (2011 Oct 4). Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex.
Stuwe T, et al. (2012 Jun 22). Molecular basis for the anchoring of proto-oncoprotein Nup98 to the cytoplasmic face of the nuclear pore complex.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG05010
EOG86T1GN
EOG8D254R
sce:absent
Genes: 3
EOG86T1GN
EOG8D254R
sce:absent
Genes: 3
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG05011
EOG8D254R
sce:NUP42
Genes: 9
EOG8D254R
sce:NUP42
Genes: 9
SGD Description
FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier and is involved in gene tethering at the nuclear periphery; interacts with Gle1p
References
Stutz F, et al. (1995 Aug 11). Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast.
Hodge CA, et al. (1999 Oct 15). Rat8p/Dbp5p is a shuttling transport factor that interacts with Rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1-1 cells.
Strahm Y, et al. (1999 Oct 15). The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr 255p.
Strässer K, et al. (2000 Aug 21). Binding of the Mex67p/Mtr2p heterodimer to FXFG, GLFG, and FG repeat nucleoporins is essential for nuclear mRNA export.
Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.
Vainberg IE, et al. (2000 Jun). Nuclear export of heat shock and non-heat-shock mRNA occurs via similar pathways.
Allen NP, et al. (2001 Aug 3). Proteomic analysis of nucleoporin interacting proteins.
Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.
Denning DP, et al. (2003 Mar 4). Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded.
Pyhtila B, et al. (2003 Oct 24). A gradient of affinity for the karyopherin Kap95p along the yeast nuclear pore complex.
Strawn LA, et al. (2004 Mar). Minimal nuclear pore complexes define FG repeat domains essential for transport.
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG05012
EOG86T1GN
sce:absent
Genes: 2
EOG86T1GN
sce:absent
Genes: 2
PomBase Description
nucleoporin Nup146
AspGD Description
Ortholog(s) have nuclear periphery localization
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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