FOG04923
EOG8GB5R4

sce:VPS9

Genes: 34

SGD Description
Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a VPS9 domain; binds ubiquitin


PomBase Description
guanyl-nucleotide exchange factor Vps901 (predicted)


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN3678, A. fumigatus Af293 : Afu4g12490, A. oryzae RIB40 : AO090009000462, Aspergillus wentii : Aspwe1_0033898 and Aspergillus sydowii : Aspsy1_0046608


References

Burd CG, et al. (1996 May). A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins.

Shih SC, et al. (2003 Mar 17). A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain.

Prag G, et al. (2003 May 30). Mechanism of ubiquitin recognition by the CUE domain of Vps9p.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG04924
EOG8GB5R4

sce:absent

Genes: 7

AspGD Description
Ortholog(s) have cytosol localization


References

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG04925
EOG8GB5R4

sce:absent

Genes: 1

PomBase Description
guanyl-nucleotide exchange factor Vps902 (predicted)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%