FOG04906
EOG8GMSJK

sce:CGR1

Genes: 26

SGD Description
Protein involved in nucleolar integrity and processing of pre-rRNA; has a role in processing rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress; relocalizes from nucleus to nucleolus upon DNA replication stress


PomBase Description
ribosome biogenesis CGR1 family (predicted)


AspGD Description
Ortholog(s) have role in establishment of cell polarity, ribosome biogenesis and nucleolus localization


References

Sun J, et al. (2001 Jan). Cgr1p, a novel nucleolar protein encoded by Saccharomyces cerevisiae orf YGL0292w.

Sun J, et al. (2001 Jun). Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans ortholog of Saccharomyces cerevisiae CGR1.

Moy TI, et al. (2002 Apr). Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis.

Caba E, et al. (2005 Aug 4). Differentiating mechanisms of toxicity using global gene expression analysis in Saccharomyces cerevisiae.

Bhabhra R, et al. (2006 Jan). Nucleolar localization of Aspergillus fumigatus CgrA is temperature-dependent.

Wade CH, et al. (2006 Mar). The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes.

Fang Y, et al. (2012 Apr). A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%