FOG04849
EOG8HMGS9

sce:BCS1

Genes: 34

SGD Description
Protein translocase and chaperone required for Complex III assembly; member of the AAA ATPase family; forms a homo-oligomeric complex in the mitochondrial inner membrane that translocates the C-terminal domain of Rip1p from the matrix across the inner membrane, and then delivers it to an assembly intermediate of respiratory Complex III in an ATP-dependent reaction; also required for assembly of the Qcr10p subunit; mutations in human homolog BCS1L linked to neonatal diseases


PomBase Description
mitochondrial Rieske ISP assembly ATPase Bcs1 (predicted)


AspGD Description
Ortholog(s) have protein transmembrane transporter activity and role in chaperone-mediated protein complex assembly, mitochondrial respiratory chain complex III assembly, protein insertion into mitochondrial membrane from inner side


References

Nobrega FG, et al. (1992 Nov). BCS1, a novel gene required for the expression of functional Rieske iron-sulfur protein in Saccharomyces cerevisiae.

Fölsch H, et al. (1996 Feb 1). Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 28 genes with posterior transmembrane prediction > 50%

FOG04850
EOG8HMGS9

sce:absent

Genes: 3

AspGD Description
Putative AAA-ATPase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG04851
EOG8HMGS9

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%