FOG04836
EOG8J0ZVN

sce:POM33

Genes: 27

SGD Description
Transmembrane nucleoporin; involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; protein abundance increases in response to DNA replication stress


PomBase Description
tetra spanning protein 1, Tts1


AspGD Description
Ortholog(s) have structural constituent of nuclear pore activity


References

Godoy C, et al. (1996 Aug). Characterization of cwl1+, a gene from Schizosaccharomyces pombe whose overexpression causes cell lysis.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Zhang D, et al. (2010 Jun 8). The cortical ER network limits the permissive zone for actomyosin ring assembly.

Chadrin A, et al. (2010 May 31). Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution.

Zhang D, et al. (2012 Nov 6). Plasma membrane tethering of the cortical ER necessitates its finely reticulated architecture.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Asakawa H, et al. (2014 Mar-Apr). Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe.

Zhang D, et al. (2014 Oct 1). Tts1, the fission yeast homologue of the TMEM33 family, functions in NE remodeling during mitosis.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%

FOG04837
EOG8J0ZVN

sce:absent

Genes: 17

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 17 genes with posterior transmembrane prediction > 50%

FOG04838
EOG8J0ZVN

sce:PER33

Genes: 4

SGD Description
Protein that localizes to the endoplasmic reticulum; also associates with the nuclear pore complex; deletion extends chronological lifespan; highly conserved across species, orthologous to human TMEM33 and paralogous to Pom33p; protein abundance increases in response to DNA replication stress


References

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Chadrin A, et al. (2010 May 31). Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%