FOG04711
EOG83R247
EOG88GTMW
EOG88PK2T
EOG8M642F
EOG8N8PMZ

sce:YIM1

Genes: 33

SGD Description
Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress


AspGD Description
Has domain(s) with predicted oxidoreductase activity, zinc ion binding activity and role in oxidation-reduction process


References

Behrens M, et al. (1991 Aug). Mitochondrial inner membrane protease 1 of Saccharomyces cerevisiae shows sequence similarity to the Escherichia coli leader peptidase.

Athenstaedt K, et al. (1999 Oct). Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae.

Birrell GW, et al. (2002 Jun 25). Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG04712
EOG8N8PMZ

sce:AST1;AST2

Genes: 11

SGD Description
Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication|Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication


References

Logghe M, et al. (1994 Aug). The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp70 stress protein genes SSA3 and SSA4.

Chang A, et al. (1995 Jan). Targeting of the yeast plasma membrane [H+]ATPase: a novel gene AST1 prevents mislocalization of mutant ATPase to the vacuole.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG04713
EOG8N8PMZ

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%