FOG04695
EOG8NVX29

sce:INN1

Genes: 28

SGD Description
Essential protein that associates with contractile actomyosin ring; required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function; activates chitin synthase activity of Chs2p during cytokinesis


PomBase Description
C2 domain protein Fic1


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN4650, A. fumigatus Af293 : Afu2g01790, A. oryzae RIB40 : AO090011000436, Aspergillus wentii : Aspwe1_0112486 and Aspergillus sydowii : Aspsy1_0059416


References

Sanchez-Diaz A, et al. (2008 Apr). Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Roberts-Galbraith RH, et al. (2009 Jan 12). The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring.

Nishihama R, et al. (2009 Jun 15). Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae.

Jendretzki A, et al. (2009 Oct). Cyk3 acts in actomyosin ring independent cytokinesis by recruiting Inn1 to the yeast bud neck.

Meitinger F, et al. (2010 Jun 1). Targeted localization of Inn1, Cyk3 and Chs2 by the mitotic-exit network regulates cytokinesis in budding yeast.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Bohnert KA, et al. (2012). Cytokinesis-based constraints on polarized cell growth in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Martín-García R, et al. (2014 Oct 1). F-BAR domain protein Rga7 collaborates with Cdc15 and Imp2 to ensure proper cytokinesis in fission yeast.

McDonald NA, et al. (2015 Dec 21). Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis.

Ren L, et al. (2015 Jan 15). The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

McDonald NA, et al. (2017 Sep 15). Nanoscale architecture of the <i>Schizosaccharomyces pombe</i> contractile ring.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%