FOG04682
EOG8GB5QG
EOG8JM68D
EOG8P2NM9

sce:PFA3

Genes: 33

SGD Description
Palmitoyltransferase for Vac8p; required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions


PomBase Description
palmitoyltransferase Pfa3 (predicted)


AspGD Description
Has domain(s) with predicted zinc ion binding activity


References

Smotrys JE, et al. (2005 Sep 26). The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG04683
EOG8P2NM9

sce:ERF2

Genes: 28

SGD Description
Subunit of a palmitoyltransferase; this complex adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole; palmitoyltransferase is composed of Erf2p and Shr5p


PomBase Description
palmitoyltransferase Erf2


AspGD Description
Putative palmitoleyltransferase; expression repressed by tunicamycin and DTT


References

Bartels DJ, et al. (1999 Oct). Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae.

Zhao L, et al. (2002 Dec 20). Erf4p and Erf2p form an endoplasmic reticulum-associated complex involved in the plasma membrane localization of yeast Ras proteins.

Lobo S, et al. (2002 Oct 25). Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Martín-Castellanos C, et al. (2005 Nov 22). A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Amorim MJ, et al. (2010 Jun 8). Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Zhang MM, et al. (2013 Jul). Quantitative control of protein S-palmitoylation regulates meiotic entry in fission yeast.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Sánchez-Mir L, et al. (2014 Jul). Rho2 palmitoylation is required for plasma membrane localization and proper signaling to the fission yeast cell integrity mitogen- activated protein kinase pathway.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Burr R, et al. (2016 Jun 3). Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 28 genes with posterior transmembrane prediction > 50%

FOG04684
EOG8P2NM9

sce:absent

Genes: 1

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%