FOG04634
EOG8Q2BZ0

sce:RAI1

Genes: 32

SGD Description
Nuclear protein with decapping endonuclease activity; targets mRNAs with unmethylated 7-methylguanosine cap structures and 5'-triphosphates; binds to and stabilizes the exoribonuclease Rat1p; required for pre-rRNA processing; relocalizes to the cytosol in response to hypoxia; homologous to human DOM3Z


PomBase Description
Dhp1p-interacting protein Din1


AspGD Description
Ortholog(s) have GDP binding, RNA pyrophosphohydrolase activity, enzyme regulator activity, phosphodiesterase decapping endonuclease activity


References

Xue Y, et al. (2000 Jun). Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p.

Shobuike T, et al. (2001 Mar 15). The dhp1(+) gene, encoding a putative nuclear 5'-->3' exoribonuclease, is required for proper chromosome segregation in fission yeast.

Das B, et al. (2003 Aug). Degradation of normal mRNA in the nucleus of Saccharomyces cerevisiae.

Sydorskyy Y, et al. (2003 Mar). Intersection of the Kap123p-mediated nuclear import and ribosome export pathways.

Kim M, et al. (2004 Nov 25). The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

Fang F, et al. (2005 Oct). Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors.

Xiang S, et al. (2009 Apr 9). Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Jiao X, et al. (2010 Sep 30). Identification of a quality-control mechanism for mRNA 5'-end capping.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Chalamcharla VR, et al. (2015 Dec 22). Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing.

Wang VY, et al. (2015 Jul 27). Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes.

Jiao X, et al. (2017 Mar 9). 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04635
EOG8Q2BZ0
EOG8S7H6R

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG04636
EOG8S7H6R

sce:absent

Genes: 4

AspGD Description
Mannitol 1-phosphate dehydrogenase (MPD); the first enzyme in the mannitol biosynthesis pathway; expression increased in sporulating mycelium suggesting mannitol biosynthesis may be developmentally regulated; expressed in vegetative hyphae


References

Singh M, et al. (1988 Mar). NADPH generation in Aspergillus nidulans: is the mannitol cycle involved?

Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.

Saykhedkar S, et al. (2012 Jul 26). A time course analysis of the extracellular proteome of Aspergillus nidulans growing on sorghum stover.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04637
EOG8Q2BZ0

sce:absent

Genes: 3

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%