FOG04630
EOG84MWBF
EOG8Q2C03

sce:VTI1

Genes: 32

SGD Description
Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways


PomBase Description
SNARE Vti1 (predicted)


AspGD Description
Ortholog(s) have SNAP receptor activity and role in Golgi to vacuole transport, intra-Golgi vesicle-mediated transport, vacuole fusion, non-autophagic, vesicle fusion


References

Lupashin VV, et al. (1997 Dec). Characterization of a novel yeast SNARE protein implicated in Golgi retrograde traffic.

von Mollard GF, et al. (1997 Jun 30). The yeast v-SNARE Vti1p mediates two vesicle transport pathways through interactions with the t-SNAREs Sed5p and Pep12p.

Holthuis JC, et al. (1998 Jan 2). Two syntaxin homologues in the TGN/endosomal system of yeast.

Fischer von Mollard G, et al. (1998 Jan 30). A human homolog can functionally replace the yeast vesicle-associated SNARE Vti1p in two vesicle transport pathways.

Fischer von Mollard G, et al. (1999 Jun). The Saccharomyces cerevisiae v-SNARE Vti1p is required for multiple membrane transport pathways to the vacuole.

Ungermann C, et al. (1999 Jun 28). Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion.

Paumet F, et al. (2001 Dec 10). A t-SNARE of the endocytic pathway must be activated for fusion.

Lewis MJ, et al. (2002 Dec). A new yeast endosomal SNARE related to mammalian syntaxin 8.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Paumet F, et al. (2004 Mar 9). The specificity of SNARE-dependent fusion is encoded in the SNARE motif.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%

FOG04631
EOG8Q2C03

sce:SCD6

Genes: 24

SGD Description
Repressor of translation initiation; binds eIF4G through its RGG domain and inhibits recruitment of the preinitiation complex; also contains an Lsm domain; may have a role in RNA processing; overproduction suppresses null mutation in clathrin heavy chain gene CHC1; forms cytoplasmic foci upon DNA replication stress


References

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04632
EOG8Q2C03

sce:absent

Genes: 3

PomBase Description
translation initiation inhibitor (predicted)


AspGD Description
Ortholog(s) have eukaryotic initiation factor 4G binding, mRNA binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%