FOG04625
EOG8Q83GK

sce:ASH1

Genes: 18

SGD Description
Component of the Rpd3L histone deacetylase complex; zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate


References

Bobola N, et al. (1996 Mar 8). Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells.

Sil A, et al. (1996 Mar 8). Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene.

Long RM, et al. (1997 Jul 18). Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.

Takizawa PA, et al. (1997 Sep 4). Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast.

Chandarlapaty S, et al. (1998 May). Ash1, a daughter cell-specific protein, is required for pseudohyphal growth of Saccharomyces cerevisiae.

Bertrand E, et al. (1998 Oct). Localization of ASH1 mRNA particles in living yeast.

Maxon ME, et al. (2001 Feb 13). Ash1p is a site-specific DNA-binding protein that actively represses transcription.

Inglis DO, et al. (2002 Dec). Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans.

Münchow S, et al. (2002 May). Characterization of Candida albicans ASH1 in Saccharomyces cerevisiae.

Carrozza MJ, et al. (2005 Nov 10). Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex.

Mulhern SM, et al. (2006 Dec). Candida albicans transcription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions.

Elson SL, et al. (2009 Sep). An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%