FOG04496
EOG8SJ41F

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04497
EOG8SJ41F

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04498
EOG8SJ41F

sce:PBI2;

Genes: 15

SGD Description
Cytosolic inhibitor of vacuolar proteinase B (PRB1); required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion; protein abundance increases in response to DNA replication stress|Protein of unknown function; similar to Pbi2p; double null mutant lacking Pbi2p and Yhr138cp exhibits highly fragmented vacuoles; protein abundance increases in response to DNA replication stress


PomBase Description
proteinase B inhibitor Pbi2


AspGD Description
Has domain(s) with predicted identical protein binding, serine-type endopeptidase activity and role in negative regulation of catalytic activity|Putative proteinase B inhibitor


References

Betz H, et al. (1975 Sep 8). Levels and turnover of the proteinase B inhibitors in yeast.

Bünning P, et al. (1977 Aug 10). Natural occurrence and chemical modification of proteinase B inhibitors from yeast.

Maier K, et al. (1979 Dec 25). Primary structure of yeast proteinase B inhibitor 2.

Schu P, et al. (1991 Apr 10). The proteinase yscB inhibitor (PB12) gene of yeast and studies on the function of its protein product.

Xu Z, et al. (1997 Jan 27). A heterodimer of thioredoxin and I(B)2 cooperates with Sec18p (NSF) to promote yeast vacuole inheritance.

Slusarewicz P, et al. (1997 May 27). I2B is a small cytosolic protein that participates in vacuole fusion.

Xu Z, et al. (1998 Jun 26). LMA1 binds to vacuoles at Sec18p (NSF), transfers upon ATP hydrolysis to a t-SNARE (Vam3p) complex, and is released during fusion.

Elazar Z, et al. (2003 Aug 18). Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%