FOG04491
EOG8STQKG

sce:NUP120

Genes: 22

SGD Description
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP160


References

Aitchison JD, et al. (1995 Dec). Nup120p: a yeast nucleoporin required for NPC distribution and mRNA transport.

Heath CV, et al. (1995 Dec). Nuclear pore complex clustering and nuclear accumulation of poly(A)+ RNA associated with mutation of the Saccharomyces cerevisiae RAT2/NUP120 gene.

Siniossoglou S, et al. (1996 Jan 26). A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.

Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Stage-Zimmermann T, et al. (2000 Nov). Factors affecting nuclear export of the 60S ribosomal subunit in vivo.

Lutzmann M, et al. (2002 Feb 1). Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

Gao H, et al. (2003 Jul 11). Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p.

Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 11 genes with posterior transmembrane prediction > 50%