FOG04472
EOG8GXD47
EOG8T76KT

sce:RKM1;EFM1

Genes: 43

SGD Description
SET-domain lysine-N-methyltransferase; catalyzes the formation of dimethyllysine residues on the large ribosomal subunit proteins L23 (Rpl23Ap and Rpl23Bp) and monomethyllysine residues on L18 (Rps18Ap and Rps18Bp)|Lysine methyltransferase; involved in the monomethylation of eEF1A (Tef1p/Tef2p); SET-domain family member; predicted involvement in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm


PomBase Description
ribosomal lysine methyltransferase Set10


References

Porras-Yakushi TR, et al. (2005 Oct 14). A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast.

Porras-Yakushi TR, et al. (2007 Apr 27). Yeast ribosomal/cytochrome c SET domain methyltransferase subfamily: identification of Rpl23ab methylation sites and recognition motifs.

Lipson RS, et al. (2010 Aug 15). Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae.

Couttas TA, et al. (2012 Apr). Methylation of translation-associated proteins in Saccharomyces cerevisiae: Identification of methylated lysines and their methyltransferases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG04473
EOG8T76KT

sce:RKM2

Genes: 30

SGD Description
Ribosomal protein lysine methyltransferase; responsible for trimethylation of the lysine residue at position 3 of Rpl12Ap and Rpl12Bp


PomBase Description
ribosomal protein lysine methyltransferase Set11


References

Porras-Yakushi TR, et al. (2006 Nov 24). A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10.

Webb KJ, et al. (2008 Dec 19). Identification of two SET domain proteins required for methylation of lysine residues in yeast ribosomal protein Rpl42ab.

Sadaie M, et al. (2008 Mar 14). A conserved SET domain methyltransferase, Set11, modifies ribosomal protein Rpl12 in fission yeast.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 8 genes with posterior transmembrane prediction > 50%

FOG04474
EOG8T76KT

sce:absent

Genes: 5

AspGD Description
Ortholog of A. nidulans FGSC A4 : AN7340, AN10583, A. fumigatus Af293 : Afu3g06400, A. niger CBS 513.88 : An11g09940 and A. oryzae RIB40 : AO090020000722|Ortholog(s) have protein-lysine N-methyltransferase activity, role in peptidyl-lysine methylation and cytosol, nucleolus localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04475
EOG8GXD47

sce:absent

Genes: 3

AspGD Description
Ortholog of Aspergillus niger ATCC 1015 : 120572-mRNA

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%