FOG04413
EOG8VT4DZ

sce:PEX19

Genes: 29

SGD Description
Chaperone and import receptor for newly-synthesized class I PMPs; binds peroxisomal membrane proteins (PMPs) in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane; interacts with Myo2p and contributes to peroxisome partitioning


PomBase Description
Pex19 protein (predicted)


AspGD Description
Has domain(s) with predicted peroxisome localization


References

Götte K, et al. (1998 Jan). Pex19p, a farnesylated protein essential for peroxisome biogenesis.

Hettema EH, et al. (2000 Jan 17). Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins.

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Eckert JH, et al. (2003 Sep 1). Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome.

Rottensteiner H, et al. (2004 Jul). Peroxisomal membrane proteins contain common Pex19p-binding sites that are an integral part of their targeting signals.

Hoepfner D, et al. (2005 Jul 15). Contribution of the endoplasmic reticulum to peroxisome formation.

Tam YY, et al. (2005 Oct 14). Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae.

Vastiau IM, et al. (2006 Jul). Farnesylation of Pex19p is not essential for peroxisome biogenesis in yeast and mammalian cells.

Girzalsky W, et al. (2006 Jul 14). Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery.

Vizeacoumar FJ, et al. (2006 May 26). Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals.

Vizeacoumar FJ, et al. (2006 May 5). The dynamin-like protein Vps1p of the yeast Saccharomyces cerevisiae associates with peroxisomes in a Pex19p-dependent manner.

Kiel JA, et al. (2006 Oct). PEX genes in fungal genomes: common, rare or redundant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%