FOG04379
EOG8W6MGH
sce:EMC5
Genes: 15
SGD DescriptionMember of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response, and also shows K1 killer toxin resistance; homologous to worm B0334.15/EMC-5, fly CG15168, human MMGT
References
Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.
Jonikas MC, et al. (2009 Mar 27). Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.