FOG04360
EOG8WDBSS

sce:IQG1

Genes: 35

SGD Description
Essential protein required for determination of budding pattern; promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family; relocalizes from bud neck to cytoplasm upon DNA replication stress


PomBase Description
IQGAP


AspGD Description
Ortholog(s) have actin binding, calmodulin binding activity


References

Epp JA, et al. (1997 Dec 1). An IQGAP-related protein controls actin-ring formation and cytokinesis in yeast.

Lippincott J, et al. (1998 Jan 26). Sequential assembly of myosin II, an IQGAP-like protein, and filamentous actin to a ring structure involved in budding yeast cytokinesis.

Osman MA, et al. (1998 Jul 27). Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton.

Shannon KB, et al. (1999 Feb). The multiple roles of Cyk1p in the assembly and function of the actomyosin ring in budding yeast.

Boyne JR, et al. (2000 Dec). Yeast myosin light chain, Mlc1p, interacts with both IQGAP and class II myosin to effect cytokinesis.

Osman MA, et al. (2002 Nov 25). Iqg1p links spatial and secretion landmarks to polarity and cytokinesis.

Sanchez-Diaz A, et al. (2008 Apr). Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast.

Li CR, et al. (2008 Nov 19). The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans.

Nett JE, et al. (2009 Jul 15). Time course global gene expression analysis of an in vivo Candida biofilm.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
10 genes with posterior transmembrane prediction > 50%


FOG04361
EOG8WDBSS

sce:absent

Genes: 10

PomBase Description
GTPase activating protein Gap1


AspGD Description
Ortholog(s) have GTPase activator activity

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
6 genes with posterior transmembrane prediction > 50%


FOG04362
EOG8WDBSS

sce:absent

Genes: 1

PomBase Description
GTPase regulator Rng2-like (predicted)


References

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Takaine M, et al. (2014 Oct 15). The meiosis-specific nuclear passenger protein is required for proper assembly of forespore membrane in fission yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%