FOG04286
EOG8Z34X4

sce:absent

Genes: 12

References

Enjalbert B, et al. (2006 Feb). Role of the Hog1 stress-activated protein kinase in the global transcriptional response to stress in the fungal pathogen Candida albicans.

Rauceo JM, et al. (2008 Jul). Regulation of the Candida albicans cell wall damage response by transcription factor Sko1 and PAS kinase Psk1.

Ramsdale M, et al. (2008 Oct). MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans.

Alonso-Monge R, et al. (2010 Jul). The Sko1 protein represses the yeast-to-hypha transition and regulates the oxidative stress response in Candida albicans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG04287
EOG8Z34X4

sce:absent

Genes: 6

AspGD Description
Putative Atf1-like transcription factor; ortholog(s) have role in cellular response to heat, cellular response to oxidative stress; expressed in germinating conidia


References

Pócsi I, et al. (2005 Dec 20). Comparison of gene expression signatures of diamide, H2O2 and menadione exposed Aspergillus nidulans cultures--linking genome-wide transcriptional changes to cellular physiology.

Aguirre J, et al. (2005 Mar). Reactive oxygen species and development in microbial eukaryotes.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Etxebeste O, et al. (2008 Jan). Basic-zipper-type transcription factor FlbB controls asexual development in Aspergillus nidulans.

Hagiwara D, et al. (2008 Oct). Characterization of bZip-type transcription factor AtfA with reference to stress responses of conidia of Aspergillus nidulans.

Miskei M, et al. (2009 Mar). Annotation of stress-response proteins in the aspergilli.

Hagiwara D, et al. (2009 Nov). Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

Colabardini AC, et al. (2010 Dec). Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response.

Balázs A, et al. (2010 Mar). AtfA bZIP-type transcription factor regulates oxidative and osmotic stress responses in Aspergillus nidulans.

Lara-Rojas F, et al. (2011 Apr). Aspergillus nidulans transcription factor AtfA interacts with the MAPK SakA to regulate general stress responses, development and spore functions.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Bok JW, et al. (2014 Nov 22). Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus.

Emri T, et al. (2015 Jun 27). Core oxidative stress response in Aspergillus nidulans.

Jaimes-Arroyo R, et al. (2015 May). The SrkA Kinase Is Part of the SakA Mitogen-Activated Protein Kinase Interactome and Regulates Stress Responses and Development in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG04288
EOG8Z34X4

sce:ACA1

Genes: 8

SGD Description
ATF/CREB family basic leucine zipper (bZIP) transcription factor; binds as a homodimer to the ATF/CREB consensus sequence TGACGTCA; important for carbon source utilization; target genes include GRE2 and COS8; ACA1 has a paralog, CST6, that arose from the whole genome duplication


PomBase Description
transcription factor Atf31|transcription factor Pcr1|transcription factor, Atf-CREB family Atf1|transcription factor, Atf-CREB family Atf21


AspGD Description
ATF/CREB family transcription factor similar to S. pombe Atf21; ortholog(s) have role in cellular response to heat, cellular response to hydrogen peroxide; expressed in germinating conidia|Protein with some similarityto Atf1 transcription factor; ortholog(s) have role in cellular response to heat, cellular response to hydrogen peroxide; expressed in germinating conidia


References

Wahls WP, et al. (1994 Apr). RNA associated with a heterodimeric protein that activates a meiotic homologous recombination hot spot: RL/RT/PCR strategy for cloning any unknown RNA or DNA.

Wahls WP, et al. (1994 Jul 15). A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.

Takeda T, et al. (1995 Dec 15). Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase.

Kanoh J, et al. (1996 Apr). Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation.

Watanabe Y, et al. (1996 Feb). Schizosaccharomyces pombe pcr1+ encodes a CREB/ATF protein involved in regulation of gene expression for sexual development.

Shiozaki K, et al. (1996 Sep 15). Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.

Wilkinson MG, et al. (1996 Sep 15). The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.

Shiozaki K, et al. (1997). Stress-activated protein kinase pathway in cell cycle control of fission yeast.

Shieh JC, et al. (1997 Apr 15). The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle.

Kon N, et al. (1997 Dec 9). Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe.

Degols G, et al. (1997 Jun). Discrete roles of the Spc1 kinase and the Atf1 transcription factor in the UV response of Schizosaccharomyces pombe.

Shieh JC, et al. (1998 Feb). The Win1 mitotic regulator is a component of the fission yeast stress-activated Sty1 MAPK pathway.

Gaits F, et al. (1998 May 15). Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast.

Toone WM, et al. (1998 May 15). Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1.

Fernández J, et al. (1998 Nov). Enhancement of neutral trehalase activity by oxidative stress in the fission yeast Schizosaccharomyces pombe.

Yamada K, et al. (1999 Aug). Schizosaccharomyces pombe homologue of glutathione peroxidase, which does not contain selenocysteine, is induced by several stresses and works as an antioxidant.

Nguyen AN, et al. (1999 Jul 1). Heat-shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases.

Nishikawa T, et al. (1999 Jul 16). The cta3+ gene that encodes a cation-transporting P-type ATPase is induced by salt stress under control of the Wis1-Sty1 MAPKK-MAPK cascade in fission yeast.

Ohmiya R, et al. (1999 Jun). A fission yeast gene (prr1(+)) that encodes a response regulator implicated in oxidative stress response.

Ohmiya R, et al. (1999 Mar). Isolation of multicopy suppressors of the calcium sensitivity of a mutant lacking the bZIP transcription factor Atf1 in fission yeast.

Nguyen AN, et al. (2000 Apr). Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase.

Nakagawa CW, et al. (2000 Feb). Role of Atf1 and Pap1 in the induction of the catalase gene of fission yeast schizosaccharomyces pombe.

Garcia-Gimeno MA, et al. (2000 Jun). Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress.

Wilkinson CR, et al. (2000 May 19). Analysis of a gene encoding Rpn10 of the fission yeast proteasome reveals that the polyubiquitin-binding site of this subunit is essential when Rpn12/Mts3 activity is compromised.

Ohmiya R, et al. (2000 Nov). The Prr1 response regulator is essential for transcription of ste11+ and for sexual development in fission yeast.

Kim M, et al. (2000 Sep 1). The stress-activated MAP kinase Sty1/Spc1 and a 3'-regulatory element mediate UV-induced expression of the uvi15(+) gene at the post-transcriptional level.

Buck V, et al. (2001 Feb). Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway.

Groenewald M, et al. (2001 Jun). Factors involved in the regulation of the Schizosaccharomyces pombe malic enzyme gene.

Janoo RT, et al. (2001 Mar). Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex.

Jeong JH, et al. (2001 May 18). Characterization of the manganese-containing superoxide dismutase and its gene regulation in stress response of Schizosaccharomyces pombe.

Wilkinson CR, et al. (2001 Oct). Proteins containing the UBA domain are able to bind to multi-ubiquitin chains.

Quinn J, et al. (2002 Mar). Distinct regulatory proteins control the graded transcriptional response to increasing H(2)O(2) levels in fission yeast Schizosaccharomyces pombe.

Taricani L, et al. (2002 Mar 22). The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein.

Spode I, et al. (2002 May 31). ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes.

Soto T, et al. (2002 Oct). Cold induces stress-activated protein kinase-mediated response in the fission yeast Schizosaccharomyces pombe.

Lee J, et al. (2002 Oct 4). Regulation and the role of Cu,Zn-containing superoxide dismutase in cell cycle progression of Schizosaccharomyces pombe.

Greenall A, et al. (2002 Sep). Role of fission yeast Tup1-like repressors and Prr1 transcription factor in response to salt stress.

Mata J, et al. (2002 Sep). The transcriptional program of meiosis and sporulation in fission yeast.

Veal EA, et al. (2002 Sep 20). Distinct roles for glutathione S-transferases in the oxidative stress response in Schizosaccharomyces pombe.

Smith DA, et al. (2002 Sep 6). The Srk1 protein kinase is a target for the Sty1 stress-activated MAPK in fission yeast.

Lim CJ, et al. (2003 Aug 31). The thioltransferase (glutaredoxin) 1 gene of fission yeast is regulated by Atf1 and Pap1.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Paredes V, et al. (2003 Jul). Different roles for the stress-activated protein kinase pathway in the regulation of trehalose metabolism in Schizosaccharomyces pombe.

Decottignies A, et al. (2003 Mar). Schizosaccharomyces pombe essential genes: a pilot study.

Kim SJ, et al. (2003 May 31). Regulation of the gene encoding glutathione synthetase from the fission yeast.

Yamada T, et al. (2004 Apr 21). Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

Davidson MK, et al. (2004 Dec 3). Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+.

Jia S, et al. (2004 Jun 25). RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins.

Oki M, et al. (2004 Mar). Barrier proteins remodel and modify chromatin to restrict silenced domains.

Paredes V, et al. (2004 May). Transcriptional and post-translational regulation of neutral trehalase in Schizosaccharomyces pombe during thermal stress.

Noma K, et al. (2004 Nov). RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing.

Stone M, et al. (2004 Nov 26). Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

Madrid M, et al. (2004 Oct 1). A cooperative role for Atf1 and Pap1 in the detoxification of the oxidative stress induced by glucose deprivation in Schizosaccharomyces pombe.

Kim HS, et al. (2004 Oct 8). Regulation of Swi6/HP1-dependent heterochromatin assembly by cooperation of components of the mitogen-activated protein kinase pathway and a histone deacetylase Clr6.

Chung WH, et al. (2004 Sep 3). Differential expression and role of two dithiol glutaredoxins Grx1 and Grx2 in Schizosaccharomyces pombe.

Pardo M, et al. (2005 Apr 15). The nuclear rim protein Amo1 is required for proper microtubule cytoskeleton organisation in fission yeast.

Rodríguez-Gabriel MA, et al. (2005 Aug). Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe.

Moon JS, et al. (2005 Aug 31). Characterization and regulation of the gene encoding monothiol glutaredoxin 3 in the fission yeast Schizosaccharomyces pombe.

Yoshida J, et al. (2005 Feb). Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe.

Wang LY, et al. (2005 May). Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.

Petersen J, et al. (2005 May 26). Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast.

Dunand-Sauthier I, et al. (2005 Nov). Stress-activated protein kinase pathway functions to support protein synthesis and translational adaptation in response to environmental stress in fission yeast.

Zuin A, et al. (2005 Nov 4). The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe.

Titz B, et al. (2006). Transcriptional activators in yeast.

Kawasaki Y, et al. (2006 Aug). Fission yeast MAP kinase is required for the increased securin-separase interaction that rescues separase mutants under stresses.

Martín V, et al. (2006 Mar). Cip1 and Cip2 are novel RNA-recognition-motif proteins that counteract Csx1 function during oxidative stress.

Wang LY, et al. (2006 May 1). The fission yeast stress MAPK cascade regulates the pmp3+ gene that encodes a highly conserved plasma membrane protein.

Rodríguez-Gabriel MA, et al. (2006 Sep). Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast.

Mata J, et al. (2007). Transcriptional regulatory network for sexual differentiation in fission yeast.

Takada H, et al. (2007 Dec). Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast.

Jiménez-Martí E, et al. (2007 Jul). The nature of the nitrogen source added to nitrogen depleted vinifications conducted by a Saccharomyces cerevisiae strain in synthetic must affects gene expression and the levels of several volatile compounds.

Kang WH, et al. (2007 Jul 24). RNA-binding protein Csx1 is phosphorylated by LAMMER kinase, Lkh1, in response to oxidative stress in Schizosaccharomyces pombe.

López-Avilés S, et al. (2008 Apr). Activation of Srk1 by the mitogen-activated protein kinase Sty1/Spc1 precedes its dissociation from the kinase and signals its degradation.

Reiter W, et al. (2008 Apr 11). Fission yeast MAP kinase Sty1 is recruited to stress-induced genes.

Asp E, et al. (2008 Feb). Fission yeast mitogen-activated protein kinase Sty1 interacts with translation factors.

Ikeda K, et al. (2008 Feb 1). Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control.

Chen D, et al. (2008 Jan). Multiple pathways differentially regulate global oxidative stress responses in fission yeast.

Sundaram G, et al. (2008 Jun). Characterization of Sro1, a novel stress responsive protein in Schizosaccharomyces pombe.

Gao J, et al. (2008 May). Distinct regions of ATF/CREB proteins Atf1 and Pcr1 control recombination hotspot ade6-M26 and the osmotic stress response.

Sansó M, et al. (2008 May). Transcription factors Pcr1 and Atf1 have distinct roles in stress- and Sty1-dependent gene regulation.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Gao J, et al. (2009). Phosphorylation-independent regulation of Atf1-promoted meiotic recombination by stress-activated, p38 kinase Spc1 of fission yeast.

Calvo IA, et al. (2009 Aug 12). Genome-wide screen of genes required for caffeine tolerance in fission yeast.

Lawrence CL, et al. (2009 Dec 1). Stress-induced phosphorylation of S. pombe Atf1 abrogates its interaction with F box protein Fbh1.

Song SH, et al. (2009 Nov). Expression of the atf1+ gene is upregulated in fission yeast under nitrosative and nutritional stresses.

Zuin A, et al. (2010 Apr). Living on the edge: stress and activation of stress responses promote lifespan extension.

Takada H, et al. (2010 Feb 15). The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast.

Zuin A, et al. (2010 Mar 3). Lifespan extension by calorie restriction relies on the Sty1 MAP kinase stress pathway.

Day AM, et al. (2010 Mar 5). Hydrogen peroxide-sensitive cysteines in the Sty1 MAPK regulate the transcriptional response to oxidative stress.

Nemoto N, et al. (2010 Nov 26). The roles of stress-activated Sty1 and Gcn2 kinases and of the protooncoprotein homologue Int6/eIF3e in responses to endogenous oxidative stress during histidine starvation.

Miwa Y, et al. (2011). Ecl1, a regulator of the chronological lifespan of Schizosaccharomyces pombe, is induced upon nitrogen starvation.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Duncan CD, et al. (2011 Dec). Widespread cotranslational formation of protein complexes.

Sukegawa Y, et al. (2011 Dec). The fission yeast stress-responsive MAPK pathway promotes meiosis via the phosphorylation of Pol II CTD in response to environmental and feedback cues.

Tian C, et al. (2011 Mar). Exploring the bZIP transcription factor regulatory network in Neurospora crassa.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Kawakami K, et al. (2012 Aug 15). A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA.

Cherkasova V, et al. (2012 Feb). Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p.

Rougemaille M, et al. (2012 Jul 10). Ers1 links HP1 to RNAi.

Zhou X, et al. (2012 Jul 6). A measurable activation of the bZIP transcription factor Atf1 in a fission yeast strain devoid of stress-activated and cell integrity mitogen-activated protein kinase (MAPK) activities.

Calvo IA, et al. (2012 Jun). The transcription factors Pap1 and Prr1 collaborate to activate antioxidant, but not drug tolerance, genes in response to H2O2.

Fernández-Vázquez J, et al. (2013). Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.

Kato H, et al. (2013). The transcription factors Atf1 and Pcr1 are essential for transcriptional induction of the extracellular maltase Agl1 in fission yeast.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Jang YJ, et al. (2013 Oct). Phosphorylations of Sds23/Psp1/Moc1 by stress-activated kinase and cAMP-dependent kinase are essential for regulating cell viability in prolonged stationary phase.

García P, et al. (2014). Binding of the transcription factor Atf1 to promoters serves as a barrier to phase nucleosome arrays and avoid cryptic transcription.

Paulo E, et al. (2014 Apr). A genetic approach to study H2O2 scavenging in fission yeast--distinct roles of peroxiredoxin and catalase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Shimasaki T, et al. (2014 Aug). Ecl1 is activated by the transcription factor Atf1 in response to H2O2 stress in Schizosaccharomyces pombe.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Togashi N, et al. (2014 Jul 15). Functional significance of nuclear export and mRNA binding of meiotic regulator Spo5 in fission yeast.

Bandyopadhyay S, et al. (2014 Jun). The basic leucine zipper domain transcription factor Atf1 directly controls Cdc13 expression and regulates mitotic entry independently of Wee1 and Cdc25 in Schizosaccharomyces pombe.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Bandyopadhyay S, et al. (2015 Dec). Genome wide transcription profiling reveals a major role for the transcription factor Atf1 in regulation of cell division in Schizosaccharomyces pombe.

Asada R, et al. (2015 Mar). Antagonistic controls of chromatin and mRNA start site selection by Tup family corepressors and the CCAAT-binding factor.

Deng X, et al. (2015 Oct 7). Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast.

Hu L, et al. (2015 Sep). Azoles activate Atf1-mediated transcription through MAP kinase pathway for antifungal effects in fission yeast.

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Swaffer MP, et al. (2016 Dec 15). CDK Substrate Phosphorylation and Ordering the Cell Cycle.

García P, et al. (2016 Jan 8). Genome-wide Screening of Regulators of Catalase Expression: ROLE OF A TRANSCRIPTION COMPLEX AND HISTONE AND tRNA MODIFICATION COMPLEXES ON ADAPTATION TO STRESS.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%