FOG04276
EOG8Z8WFW

sce:PBN1

Genes: 26

SGD Description
Component of glycosylphosphatidylinositol-mannosyltransferase I; essential component; required for the autocatalytic post-translational processing of the protease B precursor Prb1p; localizes to ER in lumenal orientation; homolog of mammalian PIG-X


PomBase Description
pig-X (predicted)


AspGD Description
Has domain(s) with predicted role in GPI anchor biosynthetic process and endoplasmic reticulum membrane localization


References

Lai MH, et al. (1997 Mar 15). Multiple copies of PBS2, MHP1 or LRE1 produce glucanase resistance and other cell wall effects in Saccharomyces cerevisiae.

Naik RR, et al. (1998 Jul). The PBN1 gene of Saccharomyces cerevisiae: an essential gene that is required for the post-translational processing of the protease B precursor.

Ashida H, et al. (2005 Mar). Mammalian PIG-X and yeast Pbn1p are the essential components of glycosylphosphatidylinositol-mannosyltransferase I.

Subramanian S, et al. (2006 Jan 24). Pbn1p: an essential endoplasmic reticulum membrane protein required for protein processing in the endoplasmic reticulum of budding yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 25 genes with posterior transmembrane prediction > 50%