FOG04238
EOG802VBK
sce:YRB1
Genes: 33
EOG802VBK
sce:YRB1
Genes: 33
SGD Description
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
PomBase Description
Ran GTPase binding protein Sbp1
AspGD Description
Spi1-GTPase binding protein
References
Kopp M, et al. (1993 Mar 5). Molecular analysis of the neutral trehalase gene from Saccharomyces cerevisiae.
Butler G, et al. (1994 Nov 22). Yeast homologue of mammalian Ran binding protein 1.
Ouspenski II, et al. (1995 Feb 3). Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast.
Schlenstedt G, et al. (1995 Nov 1). Mutants in a yeast Ran binding protein are defective in nuclear transport.
Künzler M, et al. (2000 Jun). Yeast Ran-binding protein 1 (Yrb1) shuttles between the nucleus and cytoplasm and is exported from the nucleus via a CRM1 (XPO1)-dependent pathway.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG04239
EOG802VBK
EOG8DBS08
sce:YRB2
Genes: 29
EOG802VBK
EOG8DBS08
sce:YRB2
Genes: 29
SGD Description
Protein of unknown function; involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; relocalizes to the cytosol in response to hypoxia; not essential for viability
AspGD Description
Has domain(s) with predicted role in intracellular transport
References
Taura T, et al. (1997 Dec 12). Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue.
Taura T, et al. (1998 Jun 23). A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG04240
EOG802VBK
sce:NUP2
Genes: 25
EOG802VBK
sce:NUP2
Genes: 25
SGD Description
Nucleoporin involved in nucleocytoplasmic transport; binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization
PomBase Description
nucleoporin Nup61
References
Loeb JD, et al. (1993 Feb). NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex.
Titov AA, et al. (1999 Oct 18). The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus.
Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.
Solsbacher J, et al. (2000 Nov). Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha.
Allen NP, et al. (2001 Aug 3). Proteomic analysis of nucleoporin interacting proteins.
Dilworth DJ, et al. (2001 Jun 25). Nup2p dynamically associates with the distal regions of the yeast nuclear pore complex.
Denning D, et al. (2001 Sep 3). The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex.
Allen NP, et al. (2002 Dec). Deciphering networks of protein interactions at the nuclear pore complex.
Bayliss R, et al. (2002 Dec 27). GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta.
Gilchrist D, et al. (2002 May 17). Accelerating the rate of disassembly of karyopherin.cargo complexes.
Ishii K, et al. (2002 May 31). Chromatin boundaries in budding yeast: the nuclear pore connection.
Gilchrist D, et al. (2003 Dec 19). Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm.
Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.
Denning DP, et al. (2003 Mar 4). Disorder in the nuclear pore complex: the FG repeat regions of nucleoporins are natively unfolded.
Matsuura Y, et al. (2003 Oct 15). Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import.
Pyhtila B, et al. (2003 Oct 24). A gradient of affinity for the karyopherin Kap95p along the yeast nuclear pore complex.
Strawn LA, et al. (2004 Mar). Minimal nuclear pore complexes define FG repeat domains essential for transport.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG04241
EOG802VBK
sce:absent
Genes: 1
EOG802VBK
sce:absent
Genes: 1
PomBase Description
Ran GTPase binding protein Hba1
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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