FOG04228
EOG81G1P7

sce:absent

Genes: 24

References

Alarco AM, et al. (1997 Aug 1). AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily.

Billard P, et al. (1997 Dec). Characterization of an AP-1-like transcription factor that mediates an oxidative stress response in Kluyveromyces lactis.

Alarco AM, et al. (1999 Feb). The bZip transcription factor Cap1p is involved in multidrug resistance and oxidative stress response in Candida albicans.

Zhang X, et al. (2000 May). Analysis of the oxidative stress regulation of the Candida albicans transcription factor, Cap1p.

Alonso-Monge R, et al. (2003 Apr). The Hog1 mitogen-activated protein kinase is essential in the oxidative stress response and chlamydospore formation in Candida albicans.

Enjalbert B, et al. (2003 Apr). Stress-induced gene expression in Candida albicans: absence of a general stress response.

Fradin C, et al. (2005 Apr). Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood.

Sohn K, et al. (2005 Dec). Identification and characterization of Cor33p, a novel protein implicated in tolerance towards oxidative stress in Candida albicans.

Urban C, et al. (2005 Sep). The moonlighting protein Tsa1p is implicated in oxidative stress response and in cell wall biogenesis in Candida albicans.

Wang Y, et al. (2006 Apr 1). Cap1p is involved in multiple pathways of oxidative stress response in Candida albicans.

Rognon B, et al. (2006 Dec). Identification of promoter elements responsible for the regulation of MDR1 from Candida albicans, a major facilitator transporter involved in azole resistance.

Wang Y, et al. (2007 Jan 1). Cap1p plays regulation roles in redox, energy metabolism and substance transport: an investigation on Candida albicans under normal culture condition.

Cao Y, et al. (2008 Mar). Trehalose is an important mediator of Cap1p oxidative stress response in Candida albicans.

Dai BD, et al. (2009 Aug). Baicalein induces programmed cell death in Candida albicans.

Alonso-Monge R, et al. (2009 Feb). The Hog1 MAP kinase controls respiratory metabolism in the fungal pathogen Candida albicans.

Znaidi S, et al. (2009 Jun). Identification of the Candida albicans Cap1p regulon.

Sellam A, et al. (2009 May). Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans.

Kelly J, et al. (2009 Nov). Exposure to caspofungin activates Cap and Hog pathways in Candida albicans.

Rodaki A, et al. (2009 Nov). Glucose promotes stress resistance in the fungal pathogen Candida albicans.

Garcerá A, et al. (2010 Jun). Expression of Candida albicans glutathione transferases is induced inside phagocytes and upon diverse environmental stresses.

da Silva Dantas A, et al. (2010 Oct). Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans.

Mogavero S, et al. (2011 May). Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.

Schubert S, et al. (2011 May). Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.

Sasse C, et al. (2012 Aug). Inducible and constitutive activation of two polymorphic promoter alleles of the Candida albicans multidrug efflux pump MDR1.

Patterson MJ, et al. (2013 Dec 20). Ybp1 and Gpx3 signaling in Candida albicans govern hydrogen peroxide-induced oxidation of the Cap1 transcription factor and macrophage escape.

Jain C, et al. (2013 Jan 1). The role of Candida albicans AP-1 protein against host derived ROS in in vivo models of infection.

Dai BD, et al. (2013 Jun). Cap1p attenuates the apoptosis of Candida albicans.

Kaloriti D, et al. (2014 Jul 15). Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.

Ramírez-Zavala B, et al. (2014 Sep). SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG04229
EOG81G1P7

sce:absent

Genes: 4

PomBase Description
transcription factor Pap1/Caf3


AspGD Description
Ortholog(s) have role in apoptotic process, asexual sporulation, asperthecin biosynthetic process, cellular response to cadmium ion, cellular response to drug and emericellin biosynthetic process, more


References

Asano Y, et al. (2007 Jul). Characterization of the bZip-type transcription factor NapA with reference to oxidative stress response in Aspergillus nidulans.

Hagiwara D, et al. (2008 Oct). Characterization of bZip-type transcription factor AtfA with reference to stress responses of conidia of Aspergillus nidulans.

Colabardini AC, et al. (2010 Dec). Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response.

Thön M, et al. (2010 Mar). The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes.

Tian C, et al. (2011 Mar). Exploring the bZIP transcription factor regulatory network in Neurospora crassa.

Yin WB, et al. (2013 Jan). bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans.

Bok JW, et al. (2014 Nov 22). Illumina identification of RsrA, a conserved C2H2 transcription factor coordinating the NapA mediated oxidative stress signaling pathway in Aspergillus.

Zheng H, et al. (2015 Jan 5). Redox metabolites signal polymicrobial biofilm development via the NapA oxidative stress cascade in Aspergillus.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG04230
EOG81G1P7

sce:YAP1

Genes: 2

SGD Description
Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG04231
EOG81G1P7

sce:CAD1

Genes: 1

SGD Description
AP-1-like basic leucine zipper (bZIP) transcriptional activator; involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA; CAD1 has a paralog, YAP1, that arose from the whole genome duplication

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%