FOG04165
EOG844J3D
sce:absent
Genes: 17
EOG844J3D
sce:absent
Genes: 17
References
Martínez P, et al. (2005 Nov). Divergence of Stp1 and Stp2 transcription factors in Candida albicans places virulence factors required for proper nutrient acquisition under amino acid control.
Dabas N, et al. (2008 Aug). A transcription factor regulatory cascade controls secreted aspartic protease expression in Candida albicans.
Davis MM, et al. (2011). Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG04166
EOG844J3D
sce:STP2
Genes: 14
EOG844J3D
sce:STP2
Genes: 14
SGD Description
Transcription factor; activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes; STP2 has a paralog, STP1, that arose from the whole genome duplication
References
Böhm S, et al. (1997 Jun 15). Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins.
de Boer M, et al. (2000 Feb 15). Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae.
Nielsen PS, et al. (2001 Jan). Transcriptional regulation of the Saccharomyces cerevisiae amino acid permease gene BAP2.
Andréasson C, et al. (2002 Dec 15). Receptor-mediated endoproteolytic activation of two transcription factors in yeast.
Eckert-Boulet N, et al. (2004 Jun). Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p.
Andréasson C, et al. (2004 Sep). The N-terminal regulatory domain of Stp1p is modular and, fused to an artificial transcription factor, confers full Ssy1p-Ptr3p-Ssy5p sensor control.
Martínez P, et al. (2005 Nov). Divergence of Stp1 and Stp2 transcription factors in Candida albicans places virulence factors required for proper nutrient acquisition under amino acid control.
Boban M, et al. (2006 Jun 5). Asi1 is an inner nuclear membrane protein that restricts promoter access of two latent transcription factors.
Zargari A, et al. (2007 Jan 5). Inner nuclear membrane proteins Asi1, Asi2, and Asi3 function in concert to maintain the latent properties of transcription factors Stp1 and Stp2.
Davis MM, et al. (2011). Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans.
Vylkova S, et al. (2011). The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH.
Shapiro RS, et al. (2012 Mar 20). Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise.
Langford ML, et al. (2013 Sep). Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death.
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
8 genes with posterior transmembrane prediction > 50% |
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FOG04167
EOG844J3D
sce:STP1
Genes: 7
EOG844J3D
sce:STP1
Genes: 7
SGD Description
Transcription factor; contains a N-terminal regulatory motif (RI) that acts as a cytoplasmic retention determinant and as an Asi dependent degron in the nucleus; undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing; STP1 has a paralog, STP2, that arose from the whole genome duplication
References
Wang SS, et al. (1988 Dec). Isolation of a yeast gene involved in species-specific pre-tRNA processing.
Tullin S, et al. (1991 Dec). A high-affinity uptake system for branched-chain amino acids in Saccharomyces cerevisiae.
Wang SS, et al. (1992 Jun). STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs.
Böhm S, et al. (1997 Jun 15). Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins.
Jorgensen MU, et al. (1997 Mar). STP1, a gene involved in pre-tRNA processing in yeast, is important for amino-acid uptake and transcription of the permease gene BAP2.
de Boer M, et al. (2000 Feb 15). Stp1p, Stp2p and Abf1p are involved in regulation of expression of the amino acid transporter gene BAP3 of Saccharomyces cerevisiae.
Nielsen PS, et al. (2001 Jan). Transcriptional regulation of the Saccharomyces cerevisiae amino acid permease gene BAP2.
Andréasson C, et al. (2002 Dec 15). Receptor-mediated endoproteolytic activation of two transcription factors in yeast.
Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.
Abdel-Sater F, et al. (2004 Apr). The external amino acid signaling pathway promotes activation of Stp1 and Uga35/Dal81 transcription factors for induction of the AGP1 gene in Saccharomyces cerevisiae.
Eckert-Boulet N, et al. (2004 Jun). Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p.
Abdel-Sater F, et al. (2004 Nov). Amino acid signaling in yeast: casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor.
Andréasson C, et al. (2004 Sep). The N-terminal regulatory domain of Stp1p is modular and, fused to an artificial transcription factor, confers full Ssy1p-Ptr3p-Ssy5p sensor control.
Eckert-Boulet N, et al. (2006 Jan). Deletion of RTS1, encoding a regulatory subunit of protein phosphatase 2A, results in constitutive amino acid signaling via increased Stp1p processing.
Andréasson C, et al. (2006 Jun 15). Regulation of transcription factor latency by receptor-activated proteolysis.
Boban M, et al. (2006 Jun 5). Asi1 is an inner nuclear membrane protein that restricts promoter access of two latent transcription factors.
Menant A, et al. (2006 Oct 4). Substrate-mediated remodeling of methionine transport by multiple ubiquitin-dependent mechanisms in yeast cells.
Boban M, et al. (2007 Aug). Dal81 enhances Stp1- and Stp2-dependent transcription necessitating negative modulation by inner nuclear membrane protein Asi1 in Saccharomyces cerevisiae.
Zargari A, et al. (2007 Jan 5). Inner nuclear membrane proteins Asi1, Asi2, and Asi3 function in concert to maintain the latent properties of transcription factors Stp1 and Stp2.
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG04168
EOG844J3D
sce:absent
Genes: 1
EOG844J3D
sce:absent
Genes: 1
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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