FOG04090
EOG89W0X8
sce:absent
Genes: 5
FOG04091
EOG89W0X8
sce:absent
Genes: 5
SGD DescriptionProtein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR111C is not an essential gene; forms nuclear foci upon DNA replication stress
FOG04092
EOG89W0X8
sce:MSN1
Genes: 5
SGD DescriptionTranscriptional activator; involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus; relative distribution to the nucleus increases upon DNA replication stress
References
Estruch F, et al. (1990 Dec 11). Increased dosage of the MSN1 gene restores invertase expression in yeast mutants defective in the SNF1 protein kinase.
Eide D, et al. (1992 Feb). Increased dosage of a transcriptional activator gene enhances iron-limited growth of Saccharomyces cerevisiae.
FOG04093
EOG89W0X8
sce:HOT1
Genes: 11
SGD DescriptionTranscription factor for glycerol biosynthetic genes; required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p
AspGD DescriptionProtein of unknown function
References
Rep M, et al. (1999 Aug). Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p.
Rep M, et al. (2000 Mar 24). The transcriptional response of Saccharomyces cerevisiae to osmotic shock. Hot1p and Msn2p/Msn4p are required for the induction of subsets of high osmolarity glycerol pathway-dependent genes.
Alepuz PM, et al. (2001 Apr). Stress-induced map kinase Hog1 is part of transcription activation complexes.
Alepuz PM, et al. (2003 May 15). Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II.