FOG03996
EOG8G79G1
sce:PPZ1;PPZ2
Genes: 35
EOG8G79G1
sce:PPZ1;PPZ2
Genes: 35
SGD Description
Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance|Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
PomBase Description
serine/threonine protein phosphatase Pzh1
AspGD Description
Ortholog(s) have phosphatase activity and role in cellular potassium ion homeostasis, cellular response to oxidative stress, cellular sodium ion homeostasis, dephosphorylation, regulation of ATPase activity
References
Cohen PT, et al. (1990 Aug 1). Protein serine/threonine phosphatases; an expanding family.
Da Cruz e Silva EF, et al. (1991 Jun 13). Protein phosphatase 2Bw and protein phosphatase Z are Saccharomyces cerevisiae enzymes.
Posas F, et al. (1992 Jun 15). Molecular cloning and analysis of a yeast protein phosphatase with an unusual amino-terminal region.
Hughes V, et al. (1993 Aug 15). Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress.
Lee KS, et al. (1993 Sep). A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway.
de Nadal E, et al. (1998 Jun 23). The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase.
Ruiz A, et al. (2004 Aug 13). Functional characterization of the Saccharomyces cerevisiae VHS3 gene: a regulatory subunit of the Ppz1 protein phosphatase with novel, phosphatase-unrelated functions.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Son S, et al. (2009 Apr). Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1.
Leiter É, et al. (2012 Sep). Protein phosphatase Z modulates oxidative stress response in fungi.
Chen E, et al. (2016 Aug 30). Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03997
EOG8G79G1
sce:GLC7
Genes: 35
EOG8G79G1
sce:GLC7
Genes: 35
SGD Description
Type 1 serine/threonine protein phosphatase catalytic subunit; cleavage and polyadenylation factor (CPF) component; involved in various processes including glycogen metabolism, sporulation, mitosis; accumulates at mating projections by interaction with Afr1p; interacts with many regulatory subunits; involved in regulation of the nucleocytoplasmic shuttling of Hxk2p; import into nucleus is inhibited during spindle assembly checkpoint arrest
PomBase Description
serine/threonine protein phosphatase PP1 subfamily, Dis2|serine/threonine protein phosphatase PP1 subfamily, Sds21
AspGD Description
Ortholog(s) have protein serine/threonine phosphatase activity
References
Morris NR, et al. (1989 Jun). The genetic analysis of mitosis in Aspergillus nidulans.
Doonan JH, et al. (1989 Jun 16). The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1.
Ohkura H, et al. (1989 Jun 16). The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.
Feng ZH, et al. (1991 Dec 15). The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase.
Doonan JH, et al. (1991 Oct 5). A cDNA encoding rabbit muscle protein phosphatase 1 alpha complements the Aspergillus cell cycle mutation, bimG11.
Borgia PT, et al. (1992 Jan). Roles of the orlA, tsE, and bimG genes of Aspergillus nidulans in chitin synthesis.
Doonan JH, et al. (1992 Nov). Cell division in Aspergillus.
Cannon JF, et al. (1994 Feb). Characterization of glycogen-deficient glc mutants of Saccharomyces cerevisiae.
Hughes M, et al. (1996 Sep 2). A temperature-sensitive splicing mutation in the bimG gene of Aspergillus produces an N-terminal fragment which interferes with type 1 protein phosphatase function.
Hsu JY, et al. (2000 Aug 4). Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes.
Cullen PJ, et al. (2002 Dec). The Glc7p-interacting protein Bud14p attenuates polarized growth, pheromone response, and filamentous growth in Saccharomyces cerevisiae.
Fox H, et al. (2002 Sep). Dynamic distribution of BIMG(PP1) in living hyphae of Aspergillus indicates a novel role in septum formation.
Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.
Osmani SA, et al. (2004 Apr). The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans.
Knaus M, et al. (2005 Sep 7). The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast.
Son S, et al. (2009 Apr). Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1.
Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG03998
EOG8G79G1
sce:PPQ1
Genes: 25
EOG8G79G1
sce:PPQ1
Genes: 25
SGD Description
Protein phosphatase that regulates the mating response; negatively regulates the MAP kinase signaling cascade during mating; member of the serine/threonine phosphatase PP1 family
References
Chen MX, et al. (1992 Jul 13). Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases.
Chen MX, et al. (1993 Dec 1). PPQ, a novel protein phosphatase containing a Ser + Asn-rich amino-terminal domain, is involved in the regulation of protein synthesis.
Vincent A, et al. (1994 Nov). The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension.
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| Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50% |
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FOG03999
EOG8G79G1
sce:absent
Genes: 2
EOG8G79G1
sce:absent
Genes: 2
AspGD Description
Has domain(s) with predicted hydrolase activity|Has domain(s) with predicted hydrolase activity
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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