FOG03894
EOG8PC87Q

sce:MCM1

Genes: 33

SGD Description
Transcription factor; involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes; relocalizes to the cytosol in response to hypoxia


PomBase Description
MADS-box transcription factor Map1


AspGD Description
Has domain(s) with predicted DNA binding, protein dimerization activity


References

Egel R, et al. (1973 May 28). Genes involved in mating type expression of fission yeast.

Meade JH, et al. (1976 Jun). Mating-Type Mutations in SCHIZOSACCHAROMYCES POMBE: Isolation of Mutants and Analysis of Strains with an h or h Phenotype.

Dubois E, et al. (1987). Characterization of two new genes essential for vegetative growth in Saccharomyces cerevisiae: nucleotide sequence determination and chromosome mapping.

Passmore S, et al. (1988 Dec 5). Saccharomyces cerevisiae protein involved in plasmid maintenance is necessary for mating of MAT alpha cells.

Fujioka H, et al. (1989 Jul 1). A mating-type-specific sterility gene map1 is required for transcription of a mating-type gene mat1-Pi in the fission yeast Schizosaccharomyces pombe.

Ammerer G, et al. (1990 Feb). Identification, purification, and cloning of a polypeptide (PRTF/GRM) that binds to mating-specific promoter elements in yeast.

Nielsen O, et al. (1990 May). The pat1 protein kinase controls transcription of the mating-type genes in fission yeast.

Primig M, et al. (1991 Dec). The DNA binding and oligomerization domain of MCM1 is sufficient for its interaction with other regulatory proteins.

Nielsen O, et al. (1996 Dec 13). The Schizosaccharomyces pombe map1 gene encodes an SRF/MCM1-related protein required for P-cell specific gene expression.

Yabana N, et al. (1996 Jul). Schizosaccharomyces pombe map1+ encodes a MADS-box-family protein required for cell-type-specific gene expression.

Mead J, et al. (1996 May). The yeast alpha2 and Mcm1 proteins interact through a region similar to a motif found in homeodomain proteins of higher eukaryotes.

Tan S, et al. (1998 Feb 12). Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex.

El Bakkoury M, et al. (2000 Jan). Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability.

Srikantha T, et al. (2001 Aug). The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans.

Pramila T, et al. (2002 Dec 1). Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle.

Didmon M, et al. (2002 Jul). Identifying regulators of pheromone signalling in the fission yeast Schizosaccharomyces pombe.

Rottmann M, et al. (2003 Feb). A screen in Saccharomyces cerevisiae identified CaMCM1, an essential gene in Candida albicans crucial for morphogenesis.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Buck V, et al. (2004 Nov 1). Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast.

Idiris A, et al. (2006 Jan 30). Construction of a protease-deficient strain set for the fission yeast Schizosaccharomyces pombe, useful for effective production of protease-sensitive heterologous proteins.

Mata J, et al. (2006 Oct 17). Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast.

Fujioka T, et al. (2007 Aug). MpkA-Dependent and -independent cell wall integrity signaling in Aspergillus nidulans.

González P, et al. (2007 Jan 3). Myocyte enhancing factor-2A in Alzheimer's disease: genetic analysis and association with MEF2A-polymorphisms.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Askew C, et al. (2011 Feb). The zinc cluster transcription factor Ahr1p directs Mcm1p regulation of Candida albicans adhesion.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Yamakawa Y, et al. (2013 Feb 22). Regulation of cellulolytic genes by McmA, the SRF-MADS box protein in Aspergillus nidulans.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%

FOG03895
EOG8PC87Q

sce:SMP1;RLM1

Genes: 31

SGD Description
MADS-box transcription factor involved in osmotic stress response; SMP1 has a paralog, RLM1, that arose from the whole genome duplication|MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication


AspGD Description
Conserved MADS box transcription factor


References

Watanabe Y, et al. (1995 Oct). Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway.

Dodou E, et al. (1997 Apr). The Saccharomyces cerevisiae MADS-box transcription factor Rlm1 is a target for the Mpk1 mitogen-activated protein kinase pathway.

Watanabe Y, et al. (1997 May). Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.

de Nadal E, et al. (2003 Jan). Targeting the MEF2-like transcription factor Smp1 by the stress-activated Hog1 mitogen-activated protein kinase.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Damveld RA, et al. (2005 Oct). The Aspergillus niger MADS-box transcription factor RlmA is required for cell wall reinforcement in response to cell wall stress.

Fujioka T, et al. (2007 Aug). MpkA-Dependent and -independent cell wall integrity signaling in Aspergillus nidulans.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Colabardini AC, et al. (2010 Dec). Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response.

Futagami T, et al. (2012 Mar 1). Putative cell wall integrity sensor proteins in Aspergillus nidulans.

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Kovács Z, et al. (2013 May). Effect of cell wall integrity stress and RlmA transcription factor on asexual development and autolysis in Aspergillus nidulans.

Katayama T, et al. (2015). Protein kinase C regulates the expression of cell wall-related genes in RlmA-dependent and independent manners in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG03896
EOG8PC87Q

sce:ARG80

Genes: 2

SGD Description
Transcription factor involved in regulating arginine-responsive genes; acts with Arg81p and Arg82p


References

Bercy J, et al. (1987). Regulation of arginine metabolism in Saccharomyces cerevisiae: expression of the three ARGR regulatory genes and cellular localization of their products.

Dubois E, et al. (1987 Apr). Characterization of two genes, ARGRI and ARGRIII required for specific regulation of arginine metabolism in yeast.

Qiu HF, et al. (1990 Jul). Functional analysis of ARGRI and ARGRIII regulatory proteins involved in the regulation of arginine metabolism in Saccharomyces cerevisiae.

Dubois E, et al. (1991 Apr). In vitro studies of the binding of the ARGR proteins to the ARG5,6 promoter.

Messenguy F, et al. (1991 May). Determination of the DNA-binding sequences of ARGR proteins to arginine anabolic and catabolic promoters.

El Bakkoury M, et al. (2000 Jan). Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03897
EOG8PC87Q

sce:absent

Genes: 3

PomBase Description
MADS-box transcription factor Mbx1|MADS-box transcription factor Pvg4


References

Buck V, et al. (2004 Nov 1). Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast.

Takada H, et al. (2007 Dec). Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Kwon EJ, et al. (2012). Deciphering the transcriptional-regulatory network of flocculation in Schizosaccharomyces pombe.

Matsuzawa T, et al. (2012 Feb). MADS box transcription factor Mbx2/Pvg4 regulates invasive growth and flocculation by inducing gsf2+ expression in fission yeast.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Vachon L, et al. (2013 Aug). Functional characterization of fission yeast transcription factors by overexpression analysis.

Matsuzawa T, et al. (2013 May). The zinc finger protein Gsf1 regulates Gsf2-dependent flocculation in fission yeast.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%