FOG03823
EOG8SQVJ3

sce:STE18

Genes: 17

SGD Description
G protein gamma subunit; forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling


References

Whiteway M, et al. (1989 Feb 10). The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein.

Whiteway MS, et al. (1994 Aug). Site-directed mutations altering the CAAX box of Ste18, the yeast pheromone-response pathway G gamma subunit.

Hirschman JE, et al. (1999 Nov). Dual lipid modification of the yeast ggamma subunit Ste18p determines membrane localization of Gbetagamma.

Flanary PL, et al. (2000 Jun 16). Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

Manahan CL, et al. (2000 Mar). Dual lipid modification motifs in G(alpha) and G(gamma) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Fedorova ND, et al. (2005 Dec 8). Comparative analysis of programmed cell death pathways in filamentous fungi.

Lafon A, et al. (2005 Sep). The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans.

Seo JA, et al. (2005 Sep). Multiple roles of a heterotrimeric G-protein gamma-subunit in governing growth and development of Aspergillus nidulans.

Yu JH, et al. (2006 Apr). Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans.

Seo JA, et al. (2006 Feb). The phosducin-like protein PhnA is required for Gbetagamma-mediated signaling for vegetative growth, developmental control, and toxin biosynthesis in Aspergillus nidulans.

Lafon A, et al. (2006 Jul). G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective.

Yu JH, et al. (2006 Oct). Growth and developmental control in the model and pathogenic aspergilli.

Paoletti M, et al. (2007 Aug 21). Mating type and the genetic basis of self-fertility in the model fungus Aspergillus nidulans.

Emri T, et al. (2008 Jun). Heterotrimeric G protein mediated regulation of proteinase production in Aspergillus nidulans.

Szilágyi M, et al. (2011 Dec). Extracellular proteinase formation in carbon starving Aspergillus nidulans cultures--physiological function and regulation.

Park HS, et al. (2012 Dec). Genetic control of asexual sporulation in filamentous fungi.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%