FOG03773
EOG8WM38M

sce:PEP1;VTH1;VTH2;

Genes: 48

SGD Description
Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments|Putative membrane glycoprotein; has strong similarity to Vth2p and Pep1p/Vps10p; may be involved in vacuolar protein sorting|Putative membrane glycoprotein; has strong similarity to Vth1p and Pep1p/Vps10p; may be involved in vacuolar protein sorting|Protein of unknown function; protein-protein interactions suggest a possible role in actin patch formation; YNR065C is not an essential gene


PomBase Description
sorting receptor for vacuolar proteins, Vps10


AspGD Description
Ortholog(s) have signal sequence binding activity, role in Golgi to vacuole transport, protein targeting to vacuole and Golgi apparatus localization


References

Bankaitis VA, et al. (1986 Dec). Isolation of yeast mutants defective in protein targeting to the vacuole.

Robinson JS, et al. (1988 Nov). Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases.

Marcusson EG, et al. (1994 May 20). The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene.

Cereghino JL, et al. (1995 Sep). The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization.

Cooper AA, et al. (1996 May). Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.

Westphal V, et al. (1996 May 17). Multiple pathways for vacuolar sorting of yeast proteinase A.

Jørgensen MU, et al. (1999 Mar). Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 43 genes with posterior transmembrane prediction > 50%

FOG03774
EOG8WM38M

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03775
EOG8WM38M

sce:;

Genes: 2

SGD Description
Putative protein of unknown function|Putative membrane-localized protein of unknown function

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03776
EOG8WM38M

sce:;

Genes: 3

SGD Description
Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene|Putative protein of unknown function

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%