FOG03763
EOG8XD263

sce:SMY2;SYH1

Genes: 28

SGD Description
GYF domain protein; involved in COPII vesicle formation; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; similar to S. pombe Mpd2; SMY2 has a paralog, SYH1, that arose from the whole genome duplication|Protein of unknown function that influences nuclear pore distribution; co-purifies with ribosomes; contains a GYF domain, which bind proline-rich sequences; deletion extends chronological lifespan; SYH1 has a paralog, SMY2, that arose from the whole genome duplication


PomBase Description
GYF domain protein


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN6228, A. fumigatus Af293 : Afu2g13290, A. oryzae RIB40 : AO090026000289, Aspergillus wentii : Aspwe1_0054052 and Aspergillus sydowii : Aspsy1_0058186


References

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Kofler M, et al. (2005 Nov). GYF domain proteomics reveals interaction sites in known and novel target proteins.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Fleischer TC, et al. (2006 May 15). Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%