FOG03628
EOG880GBN

sce:PUF4

Genes: 35

SGD Description
Member of the PUF protein family; PUF family is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors


PomBase Description
RNA-binding protein (predicted)


References

Chen WN, et al. (1991 Apr). The YGL023 gene encodes a putative regulatory protein.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03629
EOG880GBN

sce:PUF3

Genes: 34

SGD Description
Protein of the mitochondrial outer surface; links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins


PomBase Description
RNA-binding protein Puf3 (predicted)


AspGD Description
Has domain(s) with predicted RNA binding activity


References

Olivas W, et al. (2000 Dec 1). The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast.

Sheth U, et al. (2003 May 2). Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Gerber AP, et al. (2004 Mar). Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast.

Jackson JS Jr, et al. (2004 Oct). Recruitment of the Puf3 protein to its mRNA target for regulation of mRNA decay in yeast.

Ringnér M, et al. (2005 Dec). Folding free energies of 5'-UTRs impact post-transcriptional regulation on a genomic scale in yeast.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Houshmandi SS, et al. (2005 Nov). Yeast Puf3 mutants reveal the complexity of Puf-RNA binding and identify a loop required for regulation of mRNA decay.

García-Rodríguez LJ, et al. (2007 Jan 15). Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast.

Ulbricht RJ, et al. (2008 Feb). Puf1p acts in combination with other yeast Puf proteins to control mRNA stability.

Saint-Georges Y, et al. (2008 Jun 4). Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Lipp JJ, et al. (2015 Aug). SR protein kinases promote splicing of nonconsensus introns.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03630
EOG880GBN

sce:MPT5

Genes: 22

SGD Description
mRNA-binding protein of the PUF family; binds to the 3' UTR of specific mRNAs, including those involved in mating type switching, cell wall integrity, chronological lifespan, chromatin modification, and spindle pole body architecture; recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity


References

Kikuchi Y, et al. (1994 Oct 17). A new yeast gene, HTR1, required for growth at high temperature, is needed for recovery from mating pheromone-induced G1 arrest.

Davis CA, et al. (2000 Apr 15). Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast.

Tadauchi T, et al. (2001 Feb 1). Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF.

Gerber AP, et al. (2004 Mar). Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG03631
EOG880GBN

sce:absent

Genes: 13

PomBase Description
RNA-binding protein Mcp2|meiotic PUF family protein 1 (predicted)


AspGD Description
Has domain(s) with predicted RNA binding activity


References

Kasama T, et al. (2006 Aug). Spo5/Mug12, a putative meiosis-specific RNA-binding protein, is essential for meiotic progression and forms Mei2 dot-like nuclear foci.

Lemieux C, et al. (2009 Jun). Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03632
EOG880GBN

sce:absent

Genes: 1

PomBase Description
RNA-binding protein (predicted)


References

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%