FOG03604
EOG88W9JB

sce:REX3

Genes: 32

SGD Description
RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases


PomBase Description
exonuclease Rex3 (predicted)


AspGD Description
Ortholog(s) have mitochondrion, nucleus localization


References

van Hoof A, et al. (2000 Mar 15). Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03605
EOG88W9JB

sce:REX4

Genes: 31

SGD Description
Putative RNA exonuclease; possibly involved in pre-rRNA processing and ribosome assembly


PomBase Description
exoribonuclease Rex4 (predicted)


AspGD Description
Ortholog(s) have role in rRNA processing, ribosomal large subunit assembly and nucleolus localization


References

Eppens NA, et al. (2002 Oct 1). Deletions in the S1 domain of Rrp5p cause processing at a novel site in ITS1 of yeast pre-rRNA that depends on Rex4p.

Faber AW, et al. (2004 Dec). The RNA catabolic enzymes Rex4p, Rnt1p, and Dbr1p show genetic interaction with trans-acting factors involved in processing of ITS1 in Saccharomyces cerevisiae pre-rRNA.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Nie M, et al. (2012 Aug 24). Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03606
EOG88W9JB

sce:RNH70

Genes: 31

SGD Description
3'-5' exoribonuclease; required for maturation of 3' ends of 5S rRNA and tRNA-Arg3 from dicistronic transcripts


PomBase Description
ribonuclease H70 (predicted)


AspGD Description
Ortholog(s) have nucleus localization


References

Lee YS, et al. (1994 Feb). Molecular cloning of a gene, DHS1, which complements a drug-hypersensitive mutation of the yeast Saccharomyces cerevisiae.

Tishkoff DX, et al. (1997 Jul 8). Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2.

Fiorentini P, et al. (1997 May). Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro.

Frank P, et al. (1999 May 7). Purification of Saccharomyces cerevisiae RNase H(70) and identification of the corresponding gene.

Kirkpatrick DT, et al. (2000 Dec). Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae.

van Hoof A, et al. (2000 Mar 15). Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast.

Nariai M, et al. (2005). Synergistic defect in 60S ribosomal subunit assembly caused by a mutation of Rrs1p, a ribosomal protein L11-binding protein, and 3'-extension of 5S rRNA in Saccharomyces cerevisiae.

Cotta-Ramusino C, et al. (2005 Jan 7). Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03607
EOG88W9JB
EOG8D7WMX

sce:absent

Genes: 4

AspGD Description
Has domain(s) with predicted exonuclease activity, nucleic acid binding activity and intracellular localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03608
EOG88W9JB

sce:absent

Genes: 1

AspGD Description
Has domain(s) with predicted nucleic acid binding activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%