FOG03571
EOG8C5B1Q

sce:APM1

Genes: 34

SGD Description
Mu1-like medium subunit of the AP-1 complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; the AP-1 complex is the clathrin-associated protein complex


PomBase Description
AP-1 adaptor complex mu subunit Apm1


AspGD Description
Ortholog(s) have role in endosomal transport, vacuole fusion, non-autophagic, vesicle-mediated transport and AP-1 adaptor complex, cell division site, cell tip, cytosol, endosome, mitotic spindle pole body, nucleus localization


References

Nakayama Y, et al. (1991 Dec 5). The medium chains of the mammalian clathrin-associated proteins have a homolog in yeast.

Yeung BG, et al. (1999 Nov). Adaptor complex-independent clathrin function in yeast.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50%


FOG03572
EOG847D93
EOG8C5B1Q
EOG8V41RW

sce:APM3

Genes: 31

SGD Description
Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway


PomBase Description
AP-3 adaptor complex subunit Apm3 (predicted)


AspGD Description
Has domain(s) with predicted role in intracellular protein transport, transport, vesicle-mediated transport and clathrin adaptor complex localization


References

Panek HR, et al. (1997 Jul 16). Suppressors of YCK-encoded yeast casein kinase 1 deficiency define the four subunits of a novel clathrin AP-like complex.

Cowles CR, et al. (1997 Oct 3). The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

Rehling P, et al. (1999 Oct). Formation of AP-3 transport intermediates requires Vps41 function.

Takegawa K, et al. (2003 Oct). Vesicle-mediated protein transport pathways to the vacuole in Schizosaccharomyces pombe.

Calvo IA, et al. (2009 Aug 12). Genome-wide screen of genes required for caffeine tolerance in fission yeast.

Fang Y, et al. (2012 Apr). A genomewide screen in Schizosaccharomyces pombe for genes affecting the sensitivity of antifungal drugs that target ergosterol biosynthesis.

Chen Z, et al. (2012 Oct). A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Hoya M, et al. (2017 Feb). Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30<sup>Fft3</sup> induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG03573
EOG8C5B1Q

sce:APM4

Genes: 31

SGD Description
Cargo-binding mu subunit of AP-2; AP-2 is a heterotetrameric endocytic cargo-binding adaptor that facilitates uptake of membrane proteins during clathrin-mediated endocytosis; Apm4p is required for AP-2 function and localization, and binds cell wall stress receptor Mid2p; AP-2 is required for cell polarity responses to pheromone, nutritional status and cell wall damage in S. cerevisiae, and for hyphal growth in C. albicans; AP-2 complex is conserved in mammals


PomBase Description
AP-2 adaptor complex subunit Apm4 (predicted)


AspGD Description
Ortholog(s) have cell division site, cytosol, mitotic spindle pole body, nucleus localization


References

Yeung BG, et al. (1999 Nov). Adaptor complex-independent clathrin function in yeast.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
10 genes with posterior transmembrane prediction > 50%


FOG03574
EOG8C5B1Q
EOG8HQC2F

sce:APM2

Genes: 23

SGD Description
Protein of unknown function; homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport


References

Stepp JD, et al. (1995 Jan). A late Golgi sorting function for Saccharomyces cerevisiae Apm1p, but not for Apm2p, a second yeast clathrin AP medium chain-related protein.

Yeung BG, et al. (1999 Nov). Adaptor complex-independent clathrin function in yeast.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50%


FOG03575
EOG8V41RW

sce:absent

Genes: 7

AspGD Description
Malonyl transferase

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50%


FOG03576
EOG8C5B1Q

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%