FOG03387
EOG8FJ6TX

sce:YKT6

Genes: 32

SGD Description
Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus


PomBase Description
SNARE Ykt6 (predicted)


AspGD Description
Ortholog(s) have SNAP receptor activity, palmitoyltransferase activity


References

Tochio H, et al. (2001 Jul 27). An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p.

Nakase Y, et al. (2006 Jun). A defect in protein farnesylation suppresses a loss of Schizosaccharomyces pombe tsc2+, a homolog of the human gene predisposing to tuberous sclerosis complex.

He Y, et al. (2006 Mar). Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway.

Ma Y, et al. (2010 Sep). Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Halim A, et al. (2015 Dec 22). Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03388
EOG8FJ6TX

sce:SEC22

Genes: 31

SGD Description
R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog


PomBase Description
SNARE Sec22 (predicted)


AspGD Description
Ortholog(s) have SNAP receptor activity and role in ER to Golgi vesicle-mediated transport, retrograde vesicle-mediated transport, Golgi to ER, vesicle fusion with Golgi apparatus


References

Hasegawa H, et al. (1989 Nov-Dec). Isolation, DNA sequence and regulation of a new cell division cycle gene from the yeast Saccharomyces cerevisiae.

Dascher C, et al. (1991 Feb). Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

Parlati F, et al. (2000 Sep 14). Topological restriction of SNARE-dependent membrane fusion.

Burri L, et al. (2003 Aug 19). A SNARE required for retrograde transport to the endoplasmic reticulum.

Mossessova E, et al. (2003 Aug 22). SNARE selectivity of the COPII coat.

Dilcher M, et al. (2003 Jul 15). Use1p is a yeast SNARE protein required for retrograde traffic to the ER.

Barrowman J, et al. (2003 May 30). The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Deshpande GP, et al. (2009 May 1). Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%

FOG03389
EOG8FJ6TX

sce:SNC2;SNC1

Genes: 29

SGD Description
Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; Snc2p levels regulated by Vps45p; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC2 has a paralog, SNC1, that arose from the whole genome duplication|Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC1 has a paralog, SNC2, that arose from the whole genome duplication


PomBase Description
SNAP receptor, synaptobrevin family


AspGD Description
Predicted vesicular SNARE, involved in vesicular transport


References

Gerst JE, et al. (1992 May 15). SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.

Protopopov V, et al. (1993 Sep 10). Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Edamatsu M, et al. (2003 Feb 14). Fission yeast synaptobrevin is involved in cytokinesis and cell elongation.

Valdez-Taubas J, et al. (2005 Jul 20). Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation.

Gachet Y, et al. (2005 Sep 15). Endocytosis in fission yeast is spatially associated with the actin cytoskeleton during polarised cell growth and cytokinesis.

Roth AF, et al. (2006 Jun 2). Global analysis of protein palmitoylation in yeast.

Miyatake M, et al. (2007 Apr). Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast.

Taheri-Talesh N, et al. (2008 Apr). The tip growth apparatus of Aspergillus nidulans.

Maeda Y, et al. (2009 Feb). The Schizosaccharomyces pombe syntaxin 1 homolog, Psy1, is essential in the development of the forespore membrane.

Abenza JF, et al. (2009 Jan). Long-distance movement of Aspergillus nidulans early endosomes on microtubule tracks.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Abenza JF, et al. (2010 Aug 1). Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes.

Amorim MJ, et al. (2010 Jun 8). Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Hervás-Aguilar A, et al. (2010 Oct). Endocytic machinery protein SlaB is dispensable for polarity establishment but necessary for polarity maintenance in hyphal tip cells of Aspergillus nidulans.

Ma Y, et al. (2010 Sep). Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Pantazopoulou A, et al. (2011 Apr). Characterization of Aspergillus nidulans RabC/Rab6.

Estravís M, et al. (2011 Dec). Cdc42 regulates multiple membrane traffic events in fission yeast.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Taheri-Talesh N, et al. (2012). The functions of myosin II and myosin V homologs in tip growth and septation in Aspergillus nidulans.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Peñalva MA, et al. (2012 Jan 1). Searching for gold beyond mitosis: Mining intracellular membrane traffic in Aspergillus nidulans.

Jourdain I, et al. (2012 Nov). Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton.

Markina-Iñarrairaegui A, et al. (2013). The Aspergillus nidulans peripheral ER: disorganization by ER stress and persistence during mitosis.

Pinar M, et al. (2013 Jul). Acute inactivation of the Aspergillus nidulans Golgi membrane fusion machinery: correlation of apical extension arrest and tip swelling with cisternal disorganization.

Yamaoka T, et al. (2013 Sep). The fission yeast synaptobrevin ortholog Syb1 plays an important role in forespore membrane formation and spore maturation.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Herrero S, et al. (2014 Aug). F-box protein RcyA controls turnover of the kinesin-7 motor KipA in Aspergillus nidulans.

de Assis LJ, et al. (2015). Aspergillus nidulans protein kinase A plays an important role in cellulase production.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Lucena-Agell D, et al. (2015 Jun). Aspergillus nidulans Ambient pH Signaling Does Not Require Endocytosis.

Wang N, et al. (2016 Apr). Roles of the TRAPP-II Complex and the Exocyst in Membrane Deposition during Fission Yeast Cytokinesis.

Imada K, et al. (2016 Nov 1). The exocytic Rabs Ypt3 and Ypt2 regulate the early step of biogenesis of the spore plasma membrane in fission yeast.

Hoya M, et al. (2017 Feb). Traffic Through the Trans-Golgi Network and the Endosomal System Requires Collaboration Between Exomer and Clathrin Adaptors in Fission Yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%

FOG03390
EOG8FJ6TX

sce:absent

Genes: 17

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 17 genes with posterior transmembrane prediction > 50%

FOG03391
EOG8FJ6TX

sce:absent

Genes: 9

AspGD Description
Ortholog(s) have cell septum, fungal-type vacuole, late endosome, plasma membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 9 genes with posterior transmembrane prediction > 50%

FOG03392
EOG8FJ6TX

sce:NYV1

Genes: 5

SGD Description
v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane


References

Nichols BJ, et al. (1997 May 8). Homotypic vacuolar fusion mediated by t- and v-SNAREs.

Ungermann C, et al. (1999 Jun 28). Three v-SNAREs and two t-SNAREs, present in a pentameric cis-SNARE complex on isolated vacuoles, are essential for homotypic fusion.

Davis CA, et al. (2000 Apr 15). Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast.

Takita Y, et al. (2001 Mar 2). Inhibition of the Ca(2+)-ATPase Pmc1p by the v-SNARE protein Nyv1p.

Müller O, et al. (2002 Feb 1). The Vtc proteins in vacuole fusion: coupling NSF activity to V(0) trans-complex formation.

Merz AJ, et al. (2004 Jan 19). Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lumen.

Wen W, et al. (2006 Oct). Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%