FOG03277
EOG8Z3509

sce:MVP1

Genes: 36

SGD Description
Protein required for sorting proteins to the vacuole; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole; participates in transcription initiation and/or early elongation of specific genes; interacts with "foot domain" of RNA polymerase II; deletion results in abnormal CTD-Ser5 phosphorylation of RNA polymerase II at specific promoter regions; protein abundance increases in response to DNA replication stress


PomBase Description
sorting nexin Mvp1 (predicted)


AspGD Description
Ortholog(s) have Golgi apparatus, fungal-type vacuole membrane localization


References

Ekena K, et al. (1995 Mar). The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting.

Chibana H, et al. (2005 Aug). Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG03278
EOG8Z3509

sce:SNX3

Genes: 33

SGD Description
Sorting nexin for late-Golgi enzymes; required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p


PomBase Description
sorting nexin Snx3 (predicted)


AspGD Description
Ortholog(s) have phosphatidylinositol-3-phosphate binding activity, role in late endosome to Golgi transport, protein localization and cytosol, endosome, nucleus localization


References

Voos W, et al. (1998 Feb 9). Retrieval of resident late-Golgi membrane proteins from the prevacuolar compartment of Saccharomyces cerevisiae is dependent on the function of Grd19p.

Zhou CZ, et al. (2003 Dec 12). Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate.

Koga T, et al. (2004 Jun). Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe.

Vollert CS, et al. (2004 Nov). The phox homology (PX) domain protein interaction network in yeast.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Wartenberg D, et al. (2012 Jul 16). Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03279
EOG8Z3509

sce:SNX4

Genes: 32

SGD Description
Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p


PomBase Description
autophagy associated protein Atg24 (predicted)


AspGD Description
Sorting nexin; predicted role in autophagy


References

Harding TM, et al. (1996 Jul 26). Genetic and phenotypic overlap between autophagy and the cytoplasm to vacuole protein targeting pathway.

Nice DC, et al. (2002 Aug 16). Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy.

Hettema EH, et al. (2003 Feb 3). Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.

Klionsky DJ, et al. (2003 Oct). A unified nomenclature for yeast autophagy-related genes.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Krsmanovic T, et al. (2005 Jun). Control of Ste6 recycling by ubiquitination in the early endocytic pathway in yeast.

Strochlic TI, et al. (2007 Apr 9). Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling.

Kanki T, et al. (2008 Nov 21). Mitophagy in yeast occurs through a selective mechanism.

Kanki T, et al. (2009 Nov). A genomic screen for yeast mutants defective in selective mitochondria autophagy.

Ohashi Y, et al. (2010 Nov 15). Membrane delivery to the yeast autophagosome from the Golgi-endosomal system.

LeBlanc MA, et al. (2010 Oct 29). Lipid binding requirements for oxysterol-binding protein Kes1 inhibition of autophagy and endosome-trans-Golgi trafficking pathways.

Mendl N, et al. (2011 Apr 15). Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG03280
EOG8Z3509

sce:absent

Genes: 11

AspGD Description
Has domain(s) with predicted phosphatidylinositol binding activity and role in cell communication

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03281
EOG8Z3509

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG03282
EOG8Z3509

sce:absent

Genes: 3

PomBase Description
autophagy associated protein (predicted)

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%