FOG02850
EOG8T4BDP

sce:BSD2

Genes: 31

SGD Description
Heavy metal ion homeostasis protein; facilitates trafficking of Smf1p and Smf2p metal transporters to vacuole where they are degraded; acts as an adaptor protein with Rsp5p in the regulated endocytosis of Smf1p and is itself ubiquitylated by Rsp5p; controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification


PomBase Description
heavy metal ion homeostasis protein Bsd2 (predicted)


AspGD Description
Ortholog(s) have role in metal ion transport, protein targeting to vacuole, ubiquitin-dependent protein catabolic process and endoplasmic reticulum, fungal-type vacuole membrane localization


References

Liu XF, et al. (1994 Nov). The requirement for yeast superoxide dismutase is bypassed through mutations in BSD2, a novel metal homeostasis gene.

Liu XF, et al. (1997 May 2). Negative control of heavy metal uptake by the Saccharomyces cerevisiae BSD2 gene.

Liu XF, et al. (1999 Feb 19). Post-translation control of Nramp metal transport in yeast. Role of metal ions and the BSD2 gene.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 30 genes with posterior transmembrane prediction > 50%

FOG02851
EOG8DFN3C

sce:SNF5

Genes: 30

SGD Description
Subunit of the SWI/SNF chromatin remodeling complex; involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p; relocates to the cytosol under hypoxic conditions


PomBase Description
SWI/SNF complex subunit Snf5


AspGD Description
Ortholog(s) have role in positive regulation of cell-substrate adhesion and regulation of glucose import by regulation of transcription from RNA polymerase II promoter, more


References

Laurent BC, et al. (1990 Nov). The SNF5 protein of Saccharomyces cerevisiae is a glutamine- and proline-rich transcriptional activator that affects expression of a broad spectrum of genes.

Smith CL, et al. (2003 Feb). Structural analysis of the yeast SWI/SNF chromatin remodeling complex.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%