FOG02782
EOG8ZGMTB

sce:SPF1

Genes: 34

SGD Description
P-type ATPase, ion transporter of the ER membrane; required to maintain normal lipid composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1


PomBase Description
P-type ATPase, calcium transporting Cta4


AspGD Description
Potassium- or calcium-transporting ATPase|Potassium-transporting ATPase


References

Suzuki C, et al. (1999 May). P-type ATPase spf1 mutants show a novel resistance mechanism for the killer toxin SMKT.

Façanha AL, et al. (2002 Jun 10). The endoplasmic reticulum cation P-type ATPase Cta4p is required for control of cell shape and microtubule dynamics.

Yoshida SH, et al. (2005 Oct). The cation-transporting P-type ATPase Cta4 is required for assembly of the forespore membrane in fission yeast.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Singh NS, et al. (2011 Dec 6). SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Cohen Y, et al. (2013). The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum.

Chen JS, et al. (2013 May). Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 34 genes with posterior transmembrane prediction > 50%

FOG02783
EOG8ZGMTB

sce:YPK9

Genes: 33

SGD Description
Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome


PomBase Description
P-type ATPase P5 type (predicted)


AspGD Description
Potassium- or calcium-transporting ATPase


References

Schmidt K, et al. (2009 May 29). Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG02784
EOG8ZGMTB

sce:absent

Genes: 2

PomBase Description
Ca2+/Mn2+ transporting P-type ATPase P5 type Cta5


References

Furune T, et al. (2008 Oct). Characterization of a fission yeast P(5)-type ATPase homologue that is essential for Ca(2+)/Mn(2+ )homeostasis in the absence of P(2)-type ATPases.

Usenovic M, et al. (2012 Mar 21). Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%