FOG02730
EOG8GTHWS

sce:RSB1

Genes: 61

SGD Description
Suppressor of sphingoid LCB sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport long chain bases (LCBs) from the cytoplasmic side toward the extracytoplasmic side of the membrane


PomBase Description
RTA1-like protein


AspGD Description
Ortholog(s) have phospholipid-translocating ATPase activity and role in cellular response to drug, fatty acid transport, phospholipid translocation, sphingoid metabolic process|Has domain(s) with predicted role in response to stress and integral component of membrane localization


References

Kihara A, et al. (2002 Aug 16). Identification and characterization of a Saccharomyces cerevisiae gene, RSB1, involved in sphingoid long-chain base release.

Kihara A, et al. (2004 Nov). Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Panwar SL, et al. (2006 Mar 10). Long chain base tolerance in Saccharomyces cerevisiae is induced by retrograde signals from the mitochondria.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 61 genes with posterior transmembrane prediction > 50%

FOG02731
EOG8GTHWS

sce:RTA1;PUG1

Genes: 35

SGD Description
Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of protein; RTA1 has a paralog, YLR046C, that arose from the whole genome duplication|Plasma membrane protein involved in protoprophyrin and heme transport; roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins


AspGD Description
Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Ortholog(s) have role in heme transport and plasma membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Ortholog(s) have role in heme transport and plasma membrane localization


References

Soustre I, et al. (1996 Jul 31). Characterization of the Saccharomyces cerevisiae RTA1 gene involved in 7-aminocholesterol resistance.

Kim H, et al. (2003 Mar 21). Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Protchenko O, et al. (2008 May). Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 35 genes with posterior transmembrane prediction > 50%

FOG02732
EOG8GTHWS

sce:absent

Genes: 5

AspGD Description
Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%

FOG02733
EOG8GTHWS

sce:absent

Genes: 4

AspGD Description
Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG02734
EOG8GTHWS

sce:absent

Genes: 4

AspGD Description
Has domain(s) with predicted role in response to stress and integral component of membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG02735
EOG8GTHWS

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG02736
EOG8GTHWS

sce:absent

Genes: 19

SGD Description
Putative membrane protein; member of the fungal lipid-translocating exporter (LTE) family of proteins; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; YLR046C has a paralog, RTA1, that arose from the whole genome duplication


AspGD Description
Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization|Has domain(s) with predicted role in response to stress and integral component of membrane localization


References

Kim H, et al. (2003 Mar 21). Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 19 genes with posterior transmembrane prediction > 50%