FOG02727
EOG8P8D22

sce:TPC1

Genes: 32

SGD Description
Mitochondrial membrane transporter; mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family


PomBase Description
mitochondrial thiamine pyrophosphate transmembrane transporter (predicted)


AspGD Description
Ortholog(s) have thiamine transmembrane transporter activity, role in thiamine pyrophosphate transport and integral component of mitochondrial inner membrane localization


References

Lindhurst MJ, et al. (1993). Amish Lethal Microcephaly

el Moualij B, et al. (1997 May). Phylogenetic classification of the mitochondrial carrier family of Saccharomyces cerevisiae.

Belenkiy R, et al. (2000 Jul 31). The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein-protein interactions with other proteins.

Marobbio CM, et al. (2002 Nov 1). Identification and reconstitution of the yeast mitochondrial transporter for thiamine pyrophosphate.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Chen JS, et al. (2014 Dec 31). Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%