FOG02722
EOG84XH0N

sce:SFC1

Genes: 31

SGD Description
Mitochondrial succinate-fumarate transporter; transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization


AspGD Description
Ortholog(s) have succinate:fumarate antiporter activity, role in acetate catabolic process, carbon utilization, fatty acid catabolic process, fumarate transport, succinate transport and mitochondrion, plasma membrane localization


References

Armitt S, et al. (1976 Feb). Analysis of acetate non-utilizing (acu) mutants in Aspergillus nidulans.

Payton M, et al. (1976 May). Agar as a carbon source and its effect on the utilization of other carbon sources by acetate non-utilizing (acu) mutants of Aspergillus nidulans.

Fernández M, et al. (1994 Mar). ACR1, a gene encoding a protein related to mitochondrial carriers, is essential for acetyl-CoA synthetase activity in Saccharomyces cerevisiae.

De Lucas JR, et al. (1997 Dec). Characterization of oleate-nonutilizing mutants of Aspergillus nidulans isolated by the 3-amino-1,2,4-triazole positive selection method.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Palmieri L, et al. (1997 Nov 3). Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate.

Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.

Flipphi M, et al. (2014 Jul). The Aspergillus nidulans acuL gene encodes a mitochondrial carrier required for the utilization of carbon sources that are metabolized via the TCA cycle.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%