FOG02654
EOG8WM398
EOG8XSJ4S

sce:FET4

Genes: 16

SGD Description
Low-affinity Fe(II) transporter of the plasma membrane


PomBase Description
iron/zinc ion transmembrane transporter (predicted)


AspGD Description
Low-affinity Fe(II) transporter


References

Dix DR, et al. (1994 Oct 21). The FET4 gene encodes the low affinity Fe(II) transport protein of Saccharomyces cerevisiae.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Dainty SJ, et al. (2008 Mar). Response of Schizosaccharomyces pombe to zinc deficiency.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Chen JS, et al. (2016 Sep). Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%

FOG02655
EOG8PVMDT
EOG8XSJ4S

sce:absent

Genes: 21

AspGD Description
Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process|Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process|Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process|Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process|Has domain(s) with predicted carbohydrate binding, catalytic activity and role in carbohydrate metabolic process


References

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 9 genes with posterior transmembrane prediction > 50%

FOG02656
EOG82V70D
EOG8D2558
EOG8NVX8G
EOG8PVMDT
EOG8V9S6P

sce:COS10;COS12;COS1;COS2;COS3;COS4;COS5;COS6;COS7;COS8;COS9;;ECM34;;

Genes: 15

SGD Description
Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; may have a role in intracellular sterol transport|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies|Nuclear membrane protein; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response|Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins||Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins||Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins


References

Lussier M, et al. (1997 Oct). Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae.

Friedmann E, et al. (2002 Sep 20). YOS9, the putative yeast homolog of a gene amplified in osteosarcomas, is involved in the endoplasmic reticulum (ER)-Golgi transport of GPI-anchored proteins.

Buschhorn BA, et al. (2004 Nov 19). A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins.

Bhamidipati A, et al. (2005 Sep 16). Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen.

Kim W, et al. (2005 Sep 16). Yos9p detects and targets misfolded glycoproteins for ER-associated degradation.

Szathmary R, et al. (2005 Sep 16). Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Carvalho P, et al. (2006 Jul 28). Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Denic V, et al. (2006 Jul 28). A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation.

Carvalho P, et al. (2010 Nov 12). Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 14 genes with posterior transmembrane prediction > 50%

FOG02657
EOG84QRNQ
EOG8MCVHX
EOG8V9S6P

sce:absent

Genes: 13

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 13 genes with posterior transmembrane prediction > 50%

FOG02658
EOG8MCVHX

sce:MST28;PRM8;PRM9;UIP3;;;;MST27

Genes: 8

SGD Description
Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles; MST28 has a paralog, MST27, that arose from a segmental duplication|Pheromone-regulated protein; contains with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family; PRM8 has a paralog, PRM9, that arose from a segmental duplication|Pheromone-regulated protein; contains 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family; PRM9 has a paralog, PRM8, that arose from a segmental duplication|Putative integral membrane protein of unknown function; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family|Putative integral membrane protein; member of DUP240 gene family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS|Putative integral membrane protein; member of DUP240 gene family; YCR007C is not an essential gene|Putative integral membrane protein; member of DUP240 gene family|Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles; MST27 has a paralog, MST28, that arose from a segmental duplication


References

Feuermann M, et al. (1997 Jul). The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes.

Takahashi Y, et al. (2000 Nov). Yeast Ulp1, an Smt3-specific protease, associates with nucleoporins.

Heiman MG, et al. (2000 Oct 30). Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating.

Ito T, et al. (2001 Apr 10). A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Poirey R, et al. (2002 Jul). Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.

Sandmann T, et al. (2003 Aug). Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae.

Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.

Leh-Louis V, et al. (2004). Differential evolution of the Saccharomyces cerevisiae DUP240 paralogs and implication of recombination in phylogeny.

Wirth B, et al. (2005 Sep). Paleogenomics or the search for remnant duplicated copies of the yeast DUP240 gene family in intergenic areas.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG02659
EOG8MCVHX
EOG8V9S6P

sce:absent

Genes: 6

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG02660
EOG8V9S6P

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG02661
EOG8MCVHX

sce:absent

Genes: 2

SGD Description
Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern


References

Poirey R, et al. (2002 Jul). Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG02662
EOG8V9S6P

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%