FOG02627
EOG8NS1SC

sce:ENA1;ENA2;ENA5

Genes: 48

SGD Description
P-type ATPase sodium pump; involved in Na+ and Li+ efflux to allow salt tolerance|P-type ATPase sodium pump; involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux|Protein with similarity to P-type ATPase sodium pumps; member of the Na+ efflux ATPase family


PomBase Description
P-type ATPase, potassium exporting Cta3


AspGD Description
Ortholog(s) have calcium-transporting ATPase activity, potassium-transporting ATPase activity and role in calcium ion transmembrane transport, hyphal growth, potassium ion export across plasma membrane, sequestering of calcium ion|Has domain(s) with predicted cation-transporting ATPase activity, metal ion binding, nucleotide binding activity, role in cation transport and integral component of membrane localization


References

Mirande M, et al. (1988 Dec 5). The yeast lysyl-tRNA synthetase gene. Evidence for general amino acid control of its expression and domain structure of the encoded protein.

Rudolph HK, et al. (1989 Jul 14). The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family.

Martinez R, et al. (1991 May). A PMR2 tandem repeat with a modified C-terminus is located downstream from the KRS1 gene encoding lysyl-tRNA synthetase in Saccharomyces cerevisiae.

Garciadeblas B, et al. (1993 Jan). Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae.

Wieland J, et al. (1995 Aug 15). The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

Márquez JA, et al. (1996 Mar 11). Multiple transduction pathways regulate the sodium-extrusion gene PMR2/ENA1 during salt stress in yeast.

Benito B, et al. (1997 Sep 4). Overexpression of the sodium ATPase of Saccharomyces cerevisiae: conditions for phosphorylation from ATP and Pi.

Galagan JE, et al. (2005 Dec 22). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Hagiwara D, et al. (2008 Dec). Functional analysis of C2H2 zinc finger transcription factor CrzA involved in calcium signaling in Aspergillus nidulans.

Spielvogel A, et al. (2008 Sep 15). Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Miskei M, et al. (2009 Mar). Annotation of stress-response proteins in the aspergilli.

Balázs A, et al. (2010 Mar). AtfA bZIP-type transcription factor regulates oxidative and osmotic stress responses in Aspergillus nidulans.

Colabardini AC, et al. (2013). Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 47 genes with posterior transmembrane prediction > 50%