FOG02605
EOG89W0WG
EOG8G4F61
EOG8KKWJB

sce:absent

Genes: 26

PomBase Description
ClC chloride channel (predicted)


AspGD Description
Has domain(s) with predicted ion channel activity, voltage-gated chloride channel activity, role in chloride transport, transmembrane transport and membrane localization


References

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 26 genes with posterior transmembrane prediction > 50%

FOG02606
EOG8KKWJB

sce:GEF1

Genes: 34

SGD Description
Voltage-gated chloride channel; localized to the golgi, the endosomal system, and plasma membrane; involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels; modulates TBSV model (+) RNA virus replication by regulating copper metabolism


PomBase Description
ClC chloride channel (predicted)


AspGD Description
Has domain(s) with predicted ion channel activity, voltage-gated chloride channel activity, role in chloride transport, transmembrane transport and membrane localization


References

Greene JR, et al. (1993 Dec). The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth.

Huang ME, et al. (1994 Sep 30). A voltage-gated chloride channel in the yeast Saccharomyces cerevisiae.

Schwappach B, et al. (1998 Jun 12). Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p.

Gaxiola RA, et al. (1998 Mar 31). The yeast CLC chloride channel functions in cation homeostasis.

Flis K, et al. (2002 Jun 28). The Gef1 protein of Saccharomyces cerevisiae is associated with chloride channel activity.

Wächter A, et al. (2005 Feb 14). The yeast CLC chloride channel is proteolytically processed by the furin-like protease Kex2p in the first extracellular loop.

Metz J, et al. (2006 Jan 6). The yeast Arr4p ATPase binds the chloride transporter Gef1p when copper is available in the cytosol.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

López-Rodríguez A, et al. (2007 Dec). The product of the gene GEF1 of Saccharomyces cerevisiae transports Cl- across the plasma membrane.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Choi ES, et al. (2012 Sep). Factors that promote H3 chromatin integrity during transcription prevent promiscuous deposition of CENP-A(Cnp1) in fission yeast.

Gal C, et al. (2016 Jan). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.

Chen JS, et al. (2016 Sep). Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 34 genes with posterior transmembrane prediction > 50%