FOG02553
EOG8ZS7JP

sce:absent

Genes: 3

AspGD Description
Has domain(s) with predicted nucleobase transmembrane transporter activity, role in nucleobase transport, transmembrane transport and membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG02554
EOG8ZS7JP

sce:DAL4;FUI1;FUR4

Genes: 46

SGD Description
Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation|High affinity uridine permease, localizes to the plasma membrane; also mediates low but significant transport of the cytotoxic nucleoside analog 5-fluorouridine; not involved in uracil transport; relative distribution to the vacuole increases upon DNA replication stress|Plasma membrane localized uracil permease; expression is tightly regulated by uracil levels and environmental cues; conformational alterations induced by unfolding or substrate binding result in Rsp5p-mediated ubiquitination and degradation


PomBase Description
purine transmembrane transporter (predicted)|uracil permease


AspGD Description
Protein with similarity to uracil transport protein FUR4 of Schizosaccharomyces pombe


References

Chevallier MR, et al. (1982). Expression of the cloned uracil permease gene of Saccharomyces cerevisiae in a heterologous membrane.

Jund R, et al. (1988 Jan 15). Primary structure of the uracil transport protein of Saccharomyces cerevisiae.

Yoo HS, et al. (1992 Dec). The allantoin and uracil permease gene sequences of Saccharomyces cerevisiae are nearly identical.

de Montigny J, et al. (1998 Aug). The uracil permease of Schizosaccharomyces pombe: a representative of a family of 10 transmembrane helix transporter proteins of yeasts.

Wagner R, et al. (1998 Feb 1). The ORF YBL042 of Saccharomyces cerevisiae encodes a uridine permease.

Vickers MF, et al. (2000 Aug 25). Nucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nishino K, et al. (2015). Cell Lysis in S. pombe ura4 Mutants Is Suppressed by Loss of Functional Pub1, Which Regulates the Uracil Transporter Fur4.

Nishino K, et al. (2017 Jul). Urea enhances cell lysis of Schizosaccharomyces pombe ura4 mutants.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 46 genes with posterior transmembrane prediction > 50%

FOG02555
EOG8ZS7JP

sce:absent

Genes: 16

PomBase Description
uricil/uridine permese transmembrane transporter family (predicted)


AspGD Description
Ortholog(s) have Golgi apparatus localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%

FOG02556
EOG8RXWFQ
EOG8ZS7JP

sce:NRT1;THI72;THI7

Genes: 41

SGD Description
High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; major transporter for 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine) uptake; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity|Transporter of thiamine or related compound; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); shares sequence similarity with Thi7p|Plasma membrane transporter responsible for the uptake of thiamine; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia


AspGD Description
Has domain(s) with predicted nucleobase transmembrane transporter activity, role in nucleobase transport, transmembrane transport and membrane localization


References

Enjo F, et al. (1997 Aug 1). Isolation and characterization of a thiamin transport gene, THI10, from Saccharomyces cerevisiae.

Nosaka K, et al. (2005 Oct). Genetic regulation mediated by thiamin pyrophosphate-binding motif in Saccharomyces cerevisiae.

Mojzita D, et al. (2006 Aug). Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae.

Paluszynski JP, et al. (2006 Jul 15). Various cytosine/adenine permease homologues are involved in the toxicity of 5-fluorocytosine in Saccharomyces cerevisiae.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Amillis S, et al. (2007 May-Jun). Regulation of expression and kinetic modeling of substrate interactions of a uracil transporter in Aspergillus nidulans.

Belenky PA, et al. (2008 Mar 28). Saccharomyces cerevisiae YOR071C encodes the high affinity nicotinamide riboside transporter Nrt1.

Hamari Z, et al. (2009 Jul). Convergent evolution and orphan genes in the Fur4p-like family and characterization of a general nucleoside transporter in Aspergillus nidulans.

Lu SP, et al. (2009 Jun 19). Assimilation of endogenous nicotinamide riboside is essential for calorie restriction-mediated life span extension in Saccharomyces cerevisiae.

Lu SP, et al. (2011 Apr 22). Phosphate-responsive signaling pathway is a novel component of NAD+ metabolism in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 41 genes with posterior transmembrane prediction > 50%

FOG02557
EOG8ZS7JP

sce:absent

Genes: 8

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 8 genes with posterior transmembrane prediction > 50%

FOG02558
EOG8ZS7JP

sce:absent

Genes: 11

AspGD Description
Has domain(s) with predicted nucleobase transmembrane transporter activity, role in nucleobase transport, transmembrane transport and membrane localization


References

Amillis S, et al. (2007 May-Jun). Regulation of expression and kinetic modeling of substrate interactions of a uracil transporter in Aspergillus nidulans.

Hamari Z, et al. (2009 Jul). Convergent evolution and orphan genes in the Fur4p-like family and characterization of a general nucleoside transporter in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 11 genes with posterior transmembrane prediction > 50%

FOG02559
EOG8ZS7JP

sce:absent

Genes: 4

AspGD Description
Has domain(s) with predicted nucleobase transmembrane transporter activity, role in nucleobase transport, transmembrane transport and membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%