FOG02326
EOG8PRR5Q
PMA0
sce:absent

Genes: 7

Protein description
Plasma membrane H+-ATPase


AspGD Description
Has domain(s) with predicted cation-transporting ATPase activity, metal ion binding, nucleotide binding activity, role in cation transport and integral component of membrane localization|Has domain(s) with predicted ATPase activity, cation-transporting ATPase activity, metal ion binding, nucleotide binding activity, role in ATP biosynthetic process, cation transport and integral component of membrane localization|Has domain(s) with predicted ATPase activity, cation-transporting ATPase activity, metal ion binding, nucleotide binding activity, role in ATP biosynthetic process, cation transport and integral component of membrane localization

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG02327
EOG8PRR5Q
PMA1
sce:PMA1

Genes: 40

Protein description
Plasma membrane H+-ATPase


Parent
paralog:FOG02326


SGD Description
Plasma membrane P2-type H+-ATPase; pumps protons out of cell; major regulator of cytoplasmic pH and plasma membrane potential; long-lived protein asymmetrically distributed at plasma membrane between mother cells and buds; accumulates at high levels in mother cells during aging, buds emerge with very low levels of Pma1p, newborn cells have low levels of Pma1p; Hsp30p plays a role in Pma1p regulation; interactions with Std1p appear to propagate [GAR+]


PomBase Description
P-type proton ATPase, P3-type Pma1|P-type proton ATPase, P3-type Pma2


AspGD Description
Plasma membrane ATPase


References

Serrano R, et al. (1986 Feb 20-26). Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases.

Portillo F, et al. (1988 Jun). Dissection of functional domains of the yeast proton-pumping ATPase by directed mutagenesis.

Davis CB, et al. (1990 Jan 25). The ATP binding site of the yeast plasma membrane proton-translocating ATPase.

Miranda M, et al. (1995 May). Molecular cloning of the plasma membrane H(+)-ATPase from Kluyveromyces lactis: a single nucleotide substitution in the gene confers ethidium bromide resistance and deficiency in K+ uptake.

Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Brown JC, et al. (2009 Oct 1). A heritable switch in carbon source utilization driven by an unusual yeast prion.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 40 genes with posterior transmembrane prediction > 50%

FOG02328
EOG8PRR5Q
PMA2
sce:PMA2

Genes: 1

Protein description
Plasma membrane H+-ATPase


Parent
ohnolog:FOG02327


SGD Description
Plasma membrane H+-ATPase; isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential


References

Schlesser A, et al. (1988 Dec 25). A second transport ATPase gene in Saccharomyces cerevisiae.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%