FOG02189
EOG85DV6F
EOG8WPZK2

sce:CSH1;SUR1

Genes: 36

SGD Description
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p; CSH1 has a paralog, SUR1, that arose from the whole genome duplication|Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p; SUR1 has a paralog, CSH1, that arose from the whole genome duplication


PomBase Description
mannosyltransferase Imt2|mannosyltransferase Imt3


AspGD Description
Mannosyl-inositol phosphorylceramide (MIPC) synthase


References

Desfarges L, et al. (1993 Mar). Yeast mutants affected in viability upon starvation have a modified phospholipid composition.

Takita Y, et al. (1995 Feb 6). The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Uemura S, et al. (2003 Nov 14). Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Nakase M, et al. (2010 May 1). Mannosylinositol phosphorylceramide is a major sphingolipid component and is required for proper localization of plasma-membrane proteins in Schizosaccharomyces pombe.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Ryuko S, et al. (2012 Aug). Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 36 genes with posterior transmembrane prediction > 50%

FOG02190
EOG8WPZK2

sce:absent

Genes: 2

AspGD Description
Mannosyl-inositol phosphorylceramide (MIPC) synthase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG02191
EOG8WPZK2

sce:absent

Genes: 1

PomBase Description
mannosyltransferase Imt1


References

Nakase M, et al. (2010 May 1). Mannosylinositol phosphorylceramide is a major sphingolipid component and is required for proper localization of plasma-membrane proteins in Schizosaccharomyces pombe.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%