FOG02113
EOG8NZS86

sce:CHO2

Genes: 28

Protein description
CHO2


SGD Description
Phosphatidylethanolamine methyltransferase (PEMT); catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis


PomBase Description
phosphatidylethanolamine N-methyltransferase Cho2


AspGD Description
Phosphatidylethanolamine N-methyltransferase


References

Yamashita S, et al. (1980 Mar). Regulation of phosphatidylethanolamine methyltransferase level by myo-inositol in Saccaromyces cerevisiae.

Yamashita S, et al. (1982 Nov 15). Regulation of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae.

Kodaki T, et al. (1987 Nov 15). Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.

Summers EF, et al. (1988 Dec). Saccharomyces cerevisiae cho2 mutants are deficient in phospholipid methylation and cross-pathway regulation of inositol synthesis.

Kodaki T, et al. (1989 Nov 6). Characterization of the methyltransferases in the yeast phosphatidylethanolamine methylation pathway by selective gene disruption.

Gaynor PM, et al. (1990 Jul 16). Phosphatidylethanolamine methyltransferase and phospholipid methyltransferase activities from Saccharomyces cerevisiae. Enzymological and kinetic properties.

Kodaki T, et al. (1991 Feb). Identification of the upstream activation sequences responsible for the expression and regulation of the PEM1 and PEM2 genes encoding the enzymes of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae.

Gaynor PM, et al. (1991 Nov 11). Regulation of phosphatidylethanolamine methyltransferase and phospholipid methyltransferase by phospholipid precursors in Saccharomyces cerevisiae.

Kanipes MI, et al. (1998 Oct). The Schizosaccharomyces pombe cho1+ gene encodes a phospholipid methyltransferase.

Boumann HA, et al. (2004 Sep 24). The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Liu NN, et al. (2010 Aug). A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Bilgin M, et al. (2011 Dec). Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: a tool for monitoring PE metabolism.

Buttrick GJ, et al. (2011 Dec). Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%