FOG02029
EOG87D80K

sce:ECI1

Genes: 32

Protein description
Peroxisomal delta3,delta2-enoyl-CoA isomerase


SGD Description
Peroxisomal delta3,delta2-enoyl-CoA isomerase; hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced; ECI1 has a paralog, DCI1, that arose from the whole genome duplication


AspGD Description
Has domain(s) with predicted catalytic activity and role in metabolic process|Putative peroxisomal delta3,delta2-enoyl-CoA isomerase|Has domain(s) with predicted catalytic activity and role in metabolic process


References

Geisbrecht BV, et al. (1998 Dec 11). Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase.

Geisbrecht BV, et al. (1999 Jun 24). Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of saccharomyces cerevisiae involved in fatty acid metabolism.

Mursula AM, et al. (2000 Aug). Crystallization and X-ray diffraction analysis of peroxisomal Delta3-Delta2-enoyl-CoA isomerase from Saccharomyces cerevisiae.

Yang X, et al. (2001 Feb). Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p.

Mursula AM, et al. (2001 Jun 15). The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.

Mursula AM, et al. (2004 Jan 16). Structural studies on delta(3)-delta(2)-enoyl-CoA isomerase: the variable mode of assembly of the trimeric disks of the crotonase superfamily.

Onwukwe GU, et al. (2015 Nov). Structures of yeast peroxisomal Δ(3),Δ(2)-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 25 genes with posterior transmembrane prediction > 50%

FOG02030
EOG87D80K

sce:DCI1

Genes: 3

SGD Description
Peroxisomal protein; identification as a delta(3,5)-delta(2,4)-dienoyl-CoA isomerase involved in fatty acid metabolism is disputed; DCI1 has a paralog, ECI1, that arose from the whole genome duplication


References

Karpichev IV, et al. (1998 Nov). Global regulatory functions of Oaf1p and Pip2p (Oaf2p), transcription factors that regulate genes encoding peroxisomal proteins in Saccharomyces cerevisiae.

Gurvitz A, et al. (1999 Aug 27). Alternatives to the isomerase-dependent pathway for the beta-oxidation of oleic acid are dispensable in Saccharomyces cerevisiae. Identification of YOR180c/DCI1 encoding peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase.

Geisbrecht BV, et al. (1999 Jun 24). Preliminary characterization of Yor180Cp: identification of a novel peroxisomal protein of saccharomyces cerevisiae involved in fatty acid metabolism.

Karpichev IV, et al. (2000 Feb). Evidence for a novel pathway for the targeting of a Saccharomyces cerevisiae peroxisomal protein belonging to the isomerase/hydratase family.

Yang X, et al. (2001 Feb). Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p.

Palková Z, et al. (2002 Nov). Ammonia pulses and metabolic oscillations guide yeast colony development.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%