FOG02012
EOG8JWSZP

sce:PHS1

Genes: 35

Protein description
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane


SGD Description
Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking


PomBase Description
3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation Phs1 (predicted)


AspGD Description
Ortholog(s) have 3-hydroxyacyl-CoA dehydratase activity, enoyl-CoA hydratase activity and role in fatty acid elongation, sphingolipid biosynthetic process, vacuolar transport|Ortholog of A. nidulans FGSC A4 : AN5000, A. fumigatus Af293 : Afu4g10270, A. niger CBS 513.88 : An04g06650 and A. oryzae RIB40 : AO090003001195, AO090005001257


References

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Denic V, et al. (2007 Aug 24). A molecular caliper mechanism for determining very long-chain fatty acid length.

Kihara A, et al. (2008 Apr 25). Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 35 genes with posterior transmembrane prediction > 50%

FOG02013
EOG8JWSZP

sce:absent

Genes: 7

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG02014
EOG8JWSZP

sce:absent

Genes: 6

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%

FOG02015
EOG8JWSZP

sce:absent

Genes: 4

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%