FOG01888
EOG88W9J0
sce:ALG8
Genes: 33
EOG88W9J0
sce:ALG8
Genes: 33
Protein description
ALG8
SGD Description
Glucosyl transferase; involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p
PomBase Description
glucosyltransferase Alg8 (predicted)
AspGD Description
Ortholog(s) have endoplasmic reticulum localization
References
Runge KW, et al. (1986 Nov 25). A new yeast mutation in the glucosylation steps of the asparagine-linked glycosylation pathway. Formation of a novel asparagine-linked oligosaccharide containing two glucose residues.
Stagljar I, et al. (1994 Jun 21). New phenotype of mutations deficient in glucosylation of the lipid-linked oligosaccharide: cloning of the ALG8 locus.
Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.
Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.
Guydosh NR, et al. (2017 Sep 25). Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in <i>S. pombe</i>.
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| Phobius transmembrane predictions
33 genes with posterior transmembrane prediction > 50% |
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FOG01889
sce:absent
Genes: 1
sce:absent
Genes: 1
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG01890
EOG808KQP
EOG8GHX46
EOG8T1G3P
sce:absent
Genes: 17
EOG808KQP
EOG8GHX46
EOG8T1G3P
sce:absent
Genes: 17
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
17 genes with posterior transmembrane prediction > 50% |
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FOG01891
EOG84B8HD
EOG8K6DNF
EOG8QZ62F
sce:absent
Genes: 12
EOG84B8HD
EOG8K6DNF
EOG8QZ62F
sce:absent
Genes: 12
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
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| Phobius transmembrane predictions
7 genes with posterior transmembrane prediction > 50% |
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FOG01892
EOG84TMPS
EOG8GHX46
EOG8GMSCG
EOG8K6DNF
sce:absent
Genes: 10
EOG84TMPS
EOG8GHX46
EOG8GMSCG
EOG8K6DNF
sce:absent
Genes: 10
PomBase Description
transcription factor, zf-fungal binuclear cluster type (predicted)
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Ortholog(s) have role in conidiophore development, hyphal growth, sporocarp development involved in sexual reproduction, syncytium formation by plasma membrane fusion|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
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| Phobius transmembrane predictions
5 genes with posterior transmembrane prediction > 50% |
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FOG01893
EOG8BG79W
EOG8FJ6QQ
EOG8K6DNF
EOG8NK99J
sce:absent
Genes: 32
EOG8BG79W
EOG8FJ6QQ
EOG8K6DNF
EOG8NK99J
sce:absent
Genes: 32
References
Maicas S, et al. (2005). In silico analysis for transcription factors with Zn(II)(2)C(6) binuclear cluster DNA-binding domains in Candida albicans.
Morschhäuser J, et al. (2007 Nov). The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans.
Dunkel N, et al. (2008 Aug). Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains.
Hoehamer CF, et al. (2009 Aug). Proteomic analysis of Mrr1p- and Tac1p-associated differential protein expression in azole-resistant clinical isolates of Candida albicans.
Sellam A, et al. (2009 May). Genome-wide mapping of the coactivator Ada2p yields insight into the functional roles of SAGA/ADA complex in Candida albicans.
Chen CG, et al. (2009 Sep). Rep1p negatively regulating MDR1 efflux pump involved in drug resistance in Candida albicans.
Singh RP, et al. (2011 Jul 15). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.
Mogavero S, et al. (2011 May). Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.
Schubert S, et al. (2011 May). Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.
Sasse C, et al. (2012 Nov). The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans.
Sun N, et al. (2013 Dec). Multidrug-resistant transporter mdr1p-mediated uptake of a novel antifungal compound.
Schillig R, et al. (2013 Sep). Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation.
Lohberger A, et al. (2014 Jan). Distinct roles of Candida albicans drug resistance transcription factors TAC1, MRR1, and UPC2 in virulence.
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| Phobius transmembrane predictions
31 genes with posterior transmembrane prediction > 50% |
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FOG01894
EOG8BG79W
sce:absent
Genes: 4
EOG8BG79W
sce:absent
Genes: 4
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01895
EOG8BG79W
sce:absent
Genes: 4
EOG8BG79W
sce:absent
Genes: 4
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01896
EOG8NK99J
sce:absent
Genes: 2
EOG8NK99J
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01897
EOG8BG79W
sce:absent
Genes: 2
EOG8BG79W
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01898
EOG8GHX46
EOG8P8D0J
sce:absent
Genes: 9
EOG8GHX46
EOG8P8D0J
sce:absent
Genes: 9
PomBase Description
transcription factor, zf-fungal binuclear cluster type (predicted)
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
References
Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
9 genes with posterior transmembrane prediction > 50% |
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FOG01899
EOG8QZ62F
sce:absent
Genes: 7
EOG8QZ62F
sce:absent
Genes: 7
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
6 genes with posterior transmembrane prediction > 50% |
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FOG01900
EOG8K6DNF
sce:absent
Genes: 6
EOG8K6DNF
sce:absent
Genes: 6
References
Maicas S, et al. (2005). In silico analysis for transcription factors with Zn(II)(2)C(6) binuclear cluster DNA-binding domains in Candida albicans.
Vandeputte P, et al. (2011). In vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.
Finkel JS, et al. (2012 Feb). Portrait of Candida albicans adherence regulators.
Schillig R, et al. (2013 Sep). Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation.
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
6 genes with posterior transmembrane prediction > 50% |
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FOG01901
EOG84TMPS
EOG883BKQ
sce:absent
Genes: 5
EOG84TMPS
EOG883BKQ
sce:absent
Genes: 5
AspGD Description
Ortholog(s) have role in hyphal growth, regulation of glycogen metabolic process|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG01902
EOG8QZ62F
sce:absent
Genes: 4
EOG8QZ62F
sce:absent
Genes: 4
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01903
EOG89GHXK
EOG8BRV3P
EOG8K6DNF
sce:RDS1
Genes: 4
EOG89GHXK
EOG8BRV3P
EOG8K6DNF
sce:RDS1
Genes: 4
SGD Description
Putative zinc cluster transcription factor; involved in conferring resistance to cycloheximide
References
Bork P, et al. (1992 Jul 23). What's in a genome?
Akache B, et al. (2002 Jun 14). New regulators of drug sensitivity in the family of yeast zinc cluster proteins.
Harbison CT, et al. (2004 Sep 2). Transcriptional regulatory code of a eukaryotic genome.
Zhu C, et al. (2009 Apr). High-resolution DNA-binding specificity analysis of yeast transcription factors.
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01904
EOG8GHX46
sce:absent
Genes: 3
EOG8GHX46
sce:absent
Genes: 3
AspGD Description
Ortholog(s) have role in hyphal growth
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50% |
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FOG01905
EOG84TMPS
EOG8WH72C
sce:absent
Genes: 2
EOG84TMPS
EOG8WH72C
sce:absent
Genes: 2
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding, zinc ion binding activity|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG01906
EOG808KQP
EOG8GHX46
sce:absent
Genes: 2
EOG808KQP
EOG8GHX46
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01907
EOG84TMPS
sce:absent
Genes: 2
EOG84TMPS
sce:absent
Genes: 2
AspGD Description
Has domain(s) with predicted DNA binding, zinc ion binding activity, role in transcription, DNA-templated and nucleus localization
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG01908
EOG84TMPS
EOG88W9J0
sce:absent
Genes: 2
EOG84TMPS
EOG88W9J0
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01909
EOG8GHX46
sce:absent
Genes: 2
EOG8GHX46
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01910
EOG84TMPS
sce:absent
Genes: 2
EOG84TMPS
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50% |
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FOG01911
EOG8BG79W
sce:absent
Genes: 1
EOG8BG79W
sce:absent
Genes: 1
AspGD Description
Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG01912
EOG808KQP
sce:absent
Genes: 1
EOG808KQP
sce:absent
Genes: 1
AspGD Description
Ortholog of Aspergillus niger ATCC 1015 : 131516-mRNA and Aspergillus carbonarius ITEM 5010 : Acar5010_056433
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG01913
EOG8GHX46
sce:absent
Genes: 6
EOG8GHX46
sce:absent
Genes: 6
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated|Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
| Mitochondrial localization predictions | ||
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| Raw data
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01914
EOG84TMPS
sce:absent
Genes: 3
EOG84TMPS
sce:absent
Genes: 3
AspGD Description
Has domain(s) with predicted RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity, role in regulation of transcription, DNA-templated and nucleus localization
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50% |
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FOG01915
EOG8T1G3P
sce:absent
Genes: 1
EOG8T1G3P
sce:absent
Genes: 1
AspGD Description
Has domain(s) with predicted DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, zinc ion binding activity and role in regulation of transcription, DNA-templated, transcription, DNA-templated
| Mitochondrial localization predictions | ||
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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FOG01916
EOG851C5Q
EOG88W9J0
sce:ITC1;
Genes: 31
EOG851C5Q
EOG88W9J0
sce:ITC1;
Genes: 31
SGD Description
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex; required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1; similar to mammalian Acf1p, the regulatory subunit of the mammalian ATP-utilizing chromatin assembly and modifying factor (ACF) complex; ITC1 has a paralog, YPL216W, that arose from the whole genome duplication|Putative protein of unknown function; not an essential gene; YPL216W has a paralog, ITC1, that arose from the whole genome duplication
AspGD Description
Ortholog(s) have role in chromatin silencing at telomere, negative regulation of transcription from RNA polymerase II promoter by pheromones and CHRAC localization
References
Goldmark JP, et al. (2000 Oct 27). The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.
Gelbart ME, et al. (2001 Mar). Interactions of Isw2 chromatin remodeling complex with nucleosomal arrays: analyses using recombinant yeast histones and immobilized templates.
Fazzio TG, et al. (2001 Oct). Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression.
Sugiyama M, et al. (2001 Sep). The Saccharomyces cerevisiae Isw2p-Itc1p complex represses INO1 expression and maintains cell morphology.
Ruiz C, et al. (2003 Feb). Cell-type-dependent repression of yeast a-specific genes requires Itc1p, a subunit of the Isw2p-Itc1p chromatin remodelling complex.
McConnell AD, et al. (2004 Apr). Histone fold protein Dls1p is required for Isw2-dependent chromatin remodeling in vivo.
Iida T, et al. (2004 Jan). Noncompetitive counteractions of DNA polymerase epsilon and ISW2/yCHRAC for epigenetic inheritance of telomere position effect in Saccharomyces cerevisiae.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
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| Phobius transmembrane predictions
10 genes with posterior transmembrane prediction > 50% |
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FOG01917
EOG89GHXK
sce:absent
Genes: 1
EOG89GHXK
sce:absent
Genes: 1
SGD Description
Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene
References
Akache B, et al. (2001 May 15). Phenotypic analysis of genes encoding yeast zinc cluster proteins.
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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