FOG01862
EOG86Q5BF

sce:MVD1

Genes: 33

SGD Description
Mevalonate pyrophosphate decarboxylase; essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer


PomBase Description
diphosphomevalonate decarboxylase mvd1 (predicted)


AspGD Description
Diphosphomevalonate decarboxylase


References

Ashby MN, et al. (1992 Feb 25). COQ2 is a candidate for the structural gene encoding para-hydroxybenzoate:polyprenyltransferase.

Toth MJ, et al. (1996 Apr 5). Molecular cloning and expression of the cDNAs encoding human and yeast mevalonate pyrophosphate decarboxylase.

Bergès T, et al. (1997 Aug). The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase is essential for viability, and a single Leu-to-Pro mutation in a conserved sequence leads to thermosensitivity.

Bonanno JB, et al. (2001 Nov 6). Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 13 genes with posterior transmembrane prediction > 50%