FOG01830
EOG81C5CV

sce:QRI1

Genes: 33

SGD Description
UDP-N-acetylglucosamine pyrophosphorylase; catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis; protein abundance increases in response to DNA replication stress


PomBase Description
UDP-N-acetylglucosamine diphosphorylase Uap1/Qri1(predicted)


AspGD Description
UDP-N-acetylglucosamine pyrophosphorylase


References

Moye-Rowley WS, et al. (1989 Mar). Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

Hertle K, et al. (1991 Jun). The SNQ3 gene of Saccharomyces cerevisiae confers hyper-resistance to several functionally unrelated chemicals.

Hussain M, et al. (1991 May 15). Characterization of PDR4, a Saccharomyces cerevisiae gene that confers pleiotropic drug resistance in high-copy number: identity with YAP1, encoding a transcriptional activator [corrected].

Schnell N, et al. (1991 Sep 1). Identification and characterization of a Saccharomyces cerevisiae gene (PAR1) conferring resistance to iron chelators.

Schnell N, et al. (1992 Apr). The PAR1 (YAP1/SNQ3) gene of Saccharomyces cerevisiae, a c-jun homologue, is involved in oxygen metabolism.

Simon M, et al. (1994 Dec). Sequence of the PHO2-POL3 (CDC2) region of chromosome IV of Saccharomyces cerevisiae.

Wemmie JA, et al. (1994 May 20). Transcriptional activation mediated by the yeast AP-1 protein is required for normal cadmium tolerance.

Kuge S, et al. (1997 Apr 1). Regulation of yAP-1 nuclear localization in response to oxidative stress.

Fernandes L, et al. (1997 Dec). Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions.

Wemmie JA, et al. (1997 Mar 21). The Saccharomyces cerevisiae AP-1 protein discriminates between oxidative stress elicited by the oxidants H2O2 and diamide.

Yan C, et al. (1998 Dec 15). Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor.

Mio T, et al. (1998 Jun 5). The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism.

Vilela C, et al. (1998 Mar 1). The yeast transcription factor genes YAP1 and YAP2 are subject to differential control at the levels of both translation and mRNA stability.

Lee J, et al. (1999 Jun 4). Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast.

Gasch AP, et al. (2000 Dec). Genomic expression programs in the response of yeast cells to environmental changes.

Dumond H, et al. (2000 May). A large-scale study of Yap1p-dependent genes in normal aerobic and H2O2-stress conditions: the role of Yap1p in cell proliferation control in yeast.

Delaunay A, et al. (2000 Oct 2). H2O2 sensing through oxidation of the Yap1 transcription factor.

Isoyama T, et al. (2001 Jun 15). Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress.

Kuge S, et al. (2001 Sep). Regulation of the yeast Yap1p nuclear export signal is mediated by redox signal-induced reversible disulfide bond formation.

Cohen BA, et al. (2002 May). Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks.

Delaunay A, et al. (2002 Nov 15). A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation.

Veal EA, et al. (2003 Aug 15). Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor.

Wiatrowski HA, et al. (2003 Feb). Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae.

Azevedo D, et al. (2003 Oct 15). Two redox centers within Yap1 for H2O2 and thiol-reactive chemicals signaling.

Wood MJ, et al. (2003 Oct 21). The redox domain of the Yap1p transcription factor contains two disulfide bonds.

Wood MJ, et al. (2004 Aug 19). Structural basis for redox regulation of Yap1 transcription factor localization.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Mogensen J, et al. (2006 Aug). Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol.

Okazaki S, et al. (2007 Aug 17). Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Ma LH, et al. (2007 Oct 26). Molecular mechanism of oxidative stress perception by the Orp1 protein.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Wout PK, et al. (2009 Jul). Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Sato I, et al. (2009 Mar 20). The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Pusztahelyi T, et al. (2011 Feb). Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans.

Ouyang X, et al. (2011 Jan 1). Yap1 activation by H2O2 or thiol-reactive chemicals elicits distinct adaptive gene responses.

Kim Y, et al. (2011 Nov). Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans.

Gerke J, et al. (2012 Jun). Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%